Objective：To comprehensively evaluate the correlation of homocysteine(Hcy)with phlegm turbidity and blood stasis of coronary heart disease in syndrome differentiation of Chinese medicine in order to provide a reference for Chinese medicine syndrome objective index of coronary heart disease.Methods：Searched published literature or included dissertations for case-control studies on correlation of phlegm turbidity syndrome and blood stasis syndrome in Chinese medicine syndrome of coronary heart disease with Hcy in Chinese Journal Full-test Database，Chinese Biological Medical Disc，VIP Database，Wanfang Database，PubMed Database，Medline Database and so on.Meta-analysis was conducted via RevMan 5.0 software.Results：Nine studies were included，including 969 cases of study subjects.The result showed that Hcy levels in the blood stasis syndrome group were obviously higher than those in the normal control group，the difference being significant[WMD=9.19，95%CI(7.49，10.89)，P ＜ 0.01].Hcy levels in the phlegm turbidity syndrome group were obviously higher than those in the normal control group，the difference being significant[WMD=8.61，95%CI(7.90，9.31)，P ＜ 0.01].Conclusion：The phlegm turbidity syndrome and blood stasis syndrome of coronary heart disease have a close correlation with Hcy of high level.Limited by the discordance of criteria in original studies and by the quality and quantity of original selected studies，the above conclusions need to be further verified by large sample studies of higher quality.