Objective： To observetheclinical effect of Ruqing tang combined with western medicine therapy for breast cancer of qi-yin deficiency type and its effect on sex hormone.Methods：Selected 75 cases of patients with breast cancer of qi-yin deficiency type as study subjects，and divided them into the observation group and the control group according to random number table method，respectively 38 cases and 37 cases in each group.The control group receivedoryzanol tablets and anastrozole tablets，while the observation group additionally received Ruqing tang based on the treatment of the control group.Both groups continuously received treatment for 3 courses，with 14 days as one course.Observed the clinical effect and level changes of sex hormone which included estradiol(E2)，follicle stimulating hormone(FSH)，luteinizing hormone(LH)and prolactin(PRL).Results：After treatment，the total effective rate was 92.11%in the observation group and was 70.27%in the control group，the difference being significant(P ＜ 0.05).Levels of E2，FSH，LH and PRL in both groups were improved when compared with those before treatment，and improvements of all indexes in the observation group were better than those in the control group，differences being significant(P ＜ 0.05).Conclusion：Therapy of Ruqing tang combined with western medicine therapy can complement each other and play a synergistic role in treating patients with breast cancer of qi-yin deficiency type.The therapy can promote endocrine balance as well as improve symptoms and tolerance of endocrine therapy of patients.