Objective: To observe the clinical effect of Zhibeng tang for adenomyosis patients with abnormal uterine bleeding induced by Mirena.Methods:Divided 74 cases of adenomyosis patients who suffered abnormal uterine bleeding after intrauterine placement of Mirena into the treatment group and the control group randomly,37 cases in each group.The treatment group was given Zhibeng tang,while the control group was given oral carbazochrome tablets.Results:After treatment of three menstrual cycles,the cure rate was 8.11%and the total effective rate was 83.78%in the treatment group,while the cure rate was 5.41%and the total effective rate was 70.27%in the control group.No significant difference was found in the comparisons of cure rate and total effective rate between the two groups(P>0.05).After treatment of six menstrual cycles,the cure rate was 35.14%and the total effective rate was 94.59%in the treatment group,while the cure rate was 10.81%and the total effective rate was 78.38%in the control group.The comparisons of cure rate and total effective rate between the two groups showed significance in differences(P<0.05).After treatment of six menstrual cycles,the number of days of vaginal bleeding during menstrual period in both groups was decreased when compared with those before treatment(P<0.05).The number of days of vaginal bleeding during menstrual period in the treatment group was less than those in the control group(P<0.05).After treatment of three and six menstrual cycles,scores of pictorial blood loss assessment chart(PBAC)in both groups were decreased when compared with those before treatment(P<0.05).The PBAC scores in the treatment group were lower than those in the control group during the same period(P<0.05).There was one case of patient with removal of intrauterine device in the treatment group,the rate of removing intrauterine device being 2.70%.There were three cases of patient with removal of intrauterine device in the control group,the rate of removing intrauterine device being 8.11%.No significant difference was found in the comparison of the rate of removing intrauterine device between the two groups(P>0.05).Conclusion:Zhibeng tang can effectively shorten the duration of vaginal bleeding in patients with adenomyosis who suffered abnormal uterine bleeding after intrauterine placement of Mirena,reduce the amount of vaginal bleeding during menstrual period,as well as improve the cure rate and total effective rate,but it needs a longer treatment cycle.