Objective：To observe the clinical effect of Yangyin Qingfei tang combined with western medicine for chronic bronchitis in acute attack of yin deficiency and dryness heat type.Methods：Divided 82 cases of patients with chronic bronchitis in acute attack of yin deficiency and dryness heat type randomly into the control group and the study group，41 cases in each group.The control group was given routine western medicine for treatment，while the study group was additionally given Yangyin Qingfei tang based on the treatment of western medicine.Compared the clinical total effective rate and remission time of symptoms and signs in two groups.Observed level changes of interleukin-6(IL-6)and tumor necrosis factor(TNF-α)before and after treatment.Results：The total effective rate was 92.68%in the study group and was 75.61%in the control group，the difference being significant(P ＜ 0.05).The remission time of cough，expectoration，asthma and lung rales in the study group was all shorter than that in the control group，the difference being significant(P＜0.05).Before treatment，there was no significant difference being found in the comparison of levels of IL-6 and TNF-α in two groups(P ＞0.05).After treatment， levels of IL-6 and TNF-ɑ in two groups were decreased when compared with those before treatment，differences being significant(P＜0.05).Levels of IL-6 and TNF-α in the study group were lower than those in the control group，differences being significant(P ＜ 0.05).Conclusion：The therapy of Yangyin Qingfei tang combined with western medicine has a significant clinical effect in treating chronic bronchitis in acute attack of yin deficiency and dryness-heat type.