Objective：To observe the clinical effect of Tianwang Buxin tang combined with acupoint catgut-embedding therapy for sub-health insomnia of fire due to yin deficiency type.MethodsAdopted randomized single-blind trial， and divided 70 cases of patients with sub-health insomnia of fire due to yin deficiency type randomly into the experiment group and the control group，35 cases in each group.The experiment group receivedthe oral treatment of Tianwang Buxin tang combined with acupoint catgut-embedding therapy，while the control group received the oral treatment of Tianwang Buxin tang only.After treatment，observed the changes of scores of Pittsburgh sleep quality index(PSQI)，scores of World Health Organization quality-of-life scale(WHOQOL-BREF)， and index of polysomnography(PSG).ResultsAfter treatment， the single scores and total scores of PSQI in both group were all lower than those before treatment(P ＜ 0.05)；the total scores of sleep quality，sleep duration，daytime dysfunction and PSQI in the experiment group were all lower than those in the control group(P ＜ 0.05)；compared the total scores of the time for falling asleep，sleep efficiency and sleep disorder in the two groups，no significantdifference was found(P ＞ 0.05).After treatment，scores of physiology，psychology，environment and social relations in both groups were higher than those before treatment(P ＜ 0.05)；the four scores in the experiment group were all higher than those in the control group(P ＜ 0.05).After treatment，the total sleep maintenance time，sleep efficiency，REM and S3+S4 in both groups were all increased，comparing with those before treatment(P ＜ 0.05)，and the total number of awakening times，the total time of awakening and sleep latency were all reduced，comparing with those before treatment(P ＜ 0.05)；the total number of awakening times and the total time of awakening in the experiment group were both lower than those in the control group(P ＜ 0.05)，and REM as well as S3+S4 in the experiment group were both higher than those inthe control group(P＜0.05).ConclusionTianwang Buxin tang combined with acupoint catgut-embedding therapy can significantly improve both the sleep and quality of life in treating sub-health insomnia of fire due to yin deficiency type，with good clinical effect and high safety.Its functioning mechanism may be related to reducing the times of wakening and the awakening time as well as increasing the time of deep sleep and rapid eye movement sleep.