Objective：To observe the clinical effect of modified Shashen Maidong tang combined with western medicine for intractable cough in children with deficiency of lung yin syndrome.MethodsSelected 80 cases of children with intractable cough with deficiency of lung yin syndrome in our hospital，and divided them randomly into the control group and the observation group，40 cases in each group.The control group was given western medicine such as anti-inflammatory drugs，expectorants， antitussives and antiasthmatics for treatment， while the observation group additionally receivedmodified Shashen Maidong tang based on the treatment of the control group.After treatment，compared the clinical effect of both groups.Then recorded the onset time of medicine and disappearance time of cough in both groups before and after treatment，and calculated the recurrence rate.ResultsThe cure rate and total effective rate in the observation group were 70.0%and 95.0%respectively，while those in the control group were 22.5%and 75.0%respectively.The comparisons of the cure rate and total effective rate between the two groups respectively showed significance in differences(P＜0.01，P＜0.05).The onset time of medicine and disappearance time of cough in the observation group were both shorter than those in the control group，differences being significant(P＜0.05).The recurrence rate was 5.3%(2/38)in the observation group and 23.3%(10/30)in the control group，the difference being significant(P＜ 0.05).ConclusionWhen treating intractable cough in children with deficiency of lung yin syndrome，the therapy of modified Shashen Maidong tang combined with western medicine has better effect than the therapy of pure western medicine，for it can rapidly relieve symptoms and reduce recurrence.