Objective：To observe the clinical effect of integrated Chinese and western medicine therapy in treating chronic sinusitis in adults.MethodsDivided 75 cases of adult patients with chronic sinusitis into the observation group with 38 cases and the control group with 37 cases.Both groups receivedroutine western medicine therapy，while the observation group additionally received Chinese herbal medicine prescription.Compared the clinical effect between the two groups and the left over rate of main symptoms after treatment，and observed the quality of life by applying SF-36 scale.ResultsCompared the cure rate and total effective rate of both groups respectively，differences being significant(P＜0.05).Compared the left over rate of main symptoms in the observation group respectively to that in the control group，differences being significant(P ＜ 0.05)，nd the observation group was better than the control group.The score was(85.9±4.0)in the observation group and(74.4±5.7)in the control group，the difference being significant(P＜ 0.05).ConclusionThe overall effect of integrated Chinese and western medicine therapy is superior to that of simple western medicine treatment.