Objective：To observe the effect of Huoxue Xingnao tang on postoperative hematoma clearance rate and prognosis of patients with chronic subdural hematoma.MethodsAccording to different treatment modality，divided 70 cases of patients with chronic subdural hematoma who receivedtreatment of trepanation and drainage indwelling into two groups，35 cases in each group.Control group received basic treatment combined with routine western medicine therapy，while observation group was additionally treated with Huoxue Xingnao tang.After two months of treatment，compared curative effect of neurologic impairment，hematoma clearance rate，residual subdural hematoma，activities of daily living(ADL)，and incidence of complication of both groups.ResultsCompared curative effect of neurologic impairment in two groups，the total effective rate was 94.29%in the observation group and was 74.29%in the control group，the difference being significant(P＜0.05).Compared the hematoma clearance rate of both groups，the total effective rate was 91.43%in the observation group and was 71.43%in the control group，the difference being significant(P ＜ 0.05).Compared the residual subdural hematoma，downtrend were showed in both groups in the 30thand 60thday after operation，and the residual amount in the observation group were all lower than those in the control group，differences being significant in the intergroup comparison(P＜0.05).Compared the ADL score in both groups，there was a rising trend in the 30thand 60thday after operation，and the ADL score in the observation group was all higher than that in the control group，differences being significant in the intergroup comparison(P＜0.05).Incidence of subdural effusion and secondary intracranial hematoma in the observation group were all lower than those in the control group，differences being significant(P＜0.05).Incidence of tension pneumocephalus and death rate of the control group were higher than those of the observation group，but no significant difference being found in the intergroup com-parison(P＞0.05).ConclusionThe application of Huoxue Xingnao tang for patients with chronic subdural hematoma can evidently improve the hematoma clearance rate，reduce the residual of hematoma，promote recovery of neural functional，and improve the activities of daily living of patients as well as reduce the incidence of complication，which is worth of clinical application.