Abstract：Objective：To observe the effect of Shexiang Baoxin Pills on heart function，inflammatory reactions and adverse cardiovascular events in patients with unstable angina pectoris after percutaneous coronary intervention (PCI). Methods： A total of 120 cases of patients with unstable angina pectoris after PCI were selected and divided into the observation group and the control group according to the random number table method，with 60 cases in each group. After PCI，the control group was treated with routine western medicine including Atorvastatin Calcium Tablets， Clopidogrel Bisulfate Tablets， and Aspirin Enteric- Coated Tablets， and the observation group was additionally treated with Shexiang Baoxin Pills based on the treatment of the control group. Both groups were given treatment for 3 months and follow-up for 6 months. The clinical effects，the heart function indexes including left ventricular end diastolic diameter (LVEDD)，left ventricular end-systolic dimension (LVESD) and left ventricular ejection fraction (LVEF)，the levels of inflammatory indexes including interleukin- 6 (IL- 6) and high- sensitivity C- reactive protein (hs-CRP)，and the incidence of adverse cardiovascular events were compared in the two groups. Results： After treatment，the total clinical effective rate was 98.33% in the observation group，higher than that of 90.00% in the control group (P＜0.05). LVEDD and LVESD in the two groups were decreased when compared with those before treatment (P＜0.05)， and LVEF were increased when compared with those before treatment (P＜0.05)； LVEDD and LVESD in the observation group were lower than those in the control group (P＜0.05)，and LVEF was higher than that in the control group (P＜0.05). The levels of IL- 6 and hs-CRP in serum in the two groups were decreased when compared with those before treatment (P＜ 0.05)，and the levels of IL-6 and hs-CRP in serum in the observation group were lower than those in the control group (P＜0.05). After a 6- month follow- up，the incidence of adverse cardiovascular events was 1.67% in the observation group， lower than that of 11.67% in the control group (P＜0.05). Conclusion： Shexiang Baoxin Pills can effectively improve the heart function of patients with unstable angina pectoris after PCI，reduce the inflammatory reactions and the incidence of adverse cardiovascular events.