Abstract：Objective：To observe the clinical effect of Xuefu Zhuyu Capsules combined with Clopidogrel Bisulfate Tablets for angina pectoris of coronary heart disease (CHDA) of qi deficiency and blood stasis type. Methods：A total of 90 cases of CHDA patients of qi deficiency and blood stasis type were divided into the control group and the treatment group according to the random number table method， with 45 cases in each group. The control group was treated with Clopidogrel Bisulfate Tablets，and the treatment group was additionally treated with Xuefu Zhuyu Capsules based on the treatment of the control group. Before and after treatment， the changes in levels of heart function indexes [left ventricular ejection fraction (LVEF)， stroke volume (SV) and cardiac index (CI)]，and vascular endothelial function [endothelin (ET)，nitric oxide (NO) and brachial arterial flow-mediated dilation (FMD)] were compared between the two groups. The onset frequency of angina pectoris，nitroglycerin dosage and scores of Seattle Angina Questionnaire (SAQ) were recorded. The clinical effects and adverse reactions were analyzed. Results： The total effective rate was 95.56% in the treatment group and 80.00% in the control group，the difference being significant (P＜0.05). Before treatment，there was no significant difference being found in the comparison of levels of LVEF，SV and CI between the two groups (P＞0.05). After treatment，the above 3 heart function indexes in the two groups were increased when compared with those before treatment (P＜0.05)， and the indexes in the treatment group were higher than those in the control group (P＜0.05). Before treatment， there was no significant difference being found in the comparison of levels of ET， NO and FMD between the two groups (P＞0.05). After treatment，the ET level in the two group was decreased when compared with that before treatment (P＜0.05)， and the levels of NO and FMD were increased when compared with those before treatment (P＜0.05)；the improvement of the above indexes of vascular endothelial function in the treatment group was better than that in the control group (P＜0.05). Before treatment， there was no significant difference being found in the comparison of onset frequency of angina pectoris， nitroglycerin dosage and SAQ scores between the two groups (P＞0.05). After treatment，the onset frequency of angina pectoris and nitroglycerin dosage in the two groups were decreased when compared with those before treatment (P＜0.05)， and SAQ scores were increased when compared with those before treatment (P＜ 0.05)；the improvement of the above indexes in the treatment group was more significant than that in the control group (P＜0.05). During treatment，the incidence of adverse reactions was 4.44% in the treatment group and 17.78% in the control group，the difference being significant between the two groups (P＜0.05). Conclusion： Xuefu Zhuyu Capsules combined with Clopidogrel Bisulfate Tablets has a definite effect on CHDA of qi deficiency and blood stasis type， which can effectively improve the symptoms of angina pectoris in pationts and enhance heart function and vascular endothelial function，with good safety.