Abstract:Objective:To study the medication rules of Chinese medicinals for vestibular migraine based on data mining. Methods:Clinical literature of Chinese medicinals for vestibular migraine included from the date when the databases were established to March 2022 was searched from China Journal Full- text Database,China Biomedicial Literature Database (CBM),China Science and Technology Journal Database and Wangfang Database and used to establish a database. Descriptive analysis, association rule analysis and cluster analysis were conducted on the Chinese medicine prescriptions. Results: A total of 77 documents and 120 Chinese medicine prescriptions were included, with 86 Chinese medicinals involved and a total usage frequency up to 1 108 times. Among them,there are 5 types of Chinese medicinals used with a frequency of more than 5%,including deficiency- supplementing medicine,blood- activating and stasis- resolving medicine,liver- calming and wind- extinguishing medicine,exterior- releasing medicine and heat-clearing medicine in descending order,with a totally frequency of 79.25%;there are 23 single Chinese medicinals used for more than 20 times with a totally frequency of 66.06%,including Chuanxiong Rhizoma,Gastrodiae Rhizoma,Angelicae Dahuricae Radix,Poria,Gardeniae Fructus,Glycyrrhizae Radix et Rhizoma, Pinelliae Rhizoma, Atractylodis Macrocephalae Rhizoma, Salviae Miltiorrhizae Radix et Rhizoma,Scutellariae Radix,Bupleuri Radix,Uncariae Ramulus Cum Uncis,Jujubae Fructus,Angelicae Sinensis Radix, Acori Tatarinowii Rhizoma, Citri Reticulatae Pericarpium, Achyranthis Bidentatae Radix, Haliotidis Concha,Carthami Flos,Codonopsis Radix,Persicae Semen,Viticis Fructus and Paeoniae Radix Rubra;in terms of the nature,the Chinese medicinals with warm,cold and mild nature account the most and they are mainly sweet,bitter and acrid in taste. The major meridian entries were the liver meridian,the heart meridian, the lung meridian, the spleen meridian and the stomach meridian; based on the association rule analysis, the couplet medicine with the highest support degree is Angelicae Dahuricae Radix- Chuanxiong Rhizoma. After the cluster analysis on the Chinese medicinals used for over 20 times, the medicinals can be divided into 4 types, mainly involving Tongqiao Huoxue Decoction, Tianma Gouteng Decoction,Banxia Baizhu Tianma Decoction and Bazhen Decoction. Conclusion:Chinese medicinals for vestibular migraine is mainly to invigorate blood and resolve stasis,and extinguish wind and suppress spasm, combined with the supplement of deficiency, and usually with Tongqiao Huoxue Decoction, Tianma Gouteng Decoction, Banxia Baizhu Tianma Decoction and Bazhen Decoction as the prescriptions.