八珍益母胶囊联合屈螺酮炔雌醇片治疗药物流产后阴道出血临床研究
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R714.21

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Clinical Study on Bazhen Yimu Capsules Combined with Drospirenone and Ethinylestradiol Tablets for Vaginal Bleeding After Medical Abortion
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    摘要:

    目的:观察八珍益母胶囊联合屈螺酮炔雌醇片治疗药物流产后阴道出血的临床疗效。方法:选取100 例行药物流产的患者为研究对象,按随机数字表法分为观察组和对照组,每组50 例。2 组均使用米非司酮联合米索前列醇进行药物流产,对照组孕囊排出后给予屈螺酮炔雌醇片治疗,观察组在此基础上加用八珍益母胶囊,治疗3 周。治疗后记录并比较2 组阴道出血量多于月经量时间、阴道出血持续时间、月经复潮时间、清宫人数、腹痛及不良反应发生情况。结果:观察组阴道出血量多于月经量时间、阴道出血持续时间及月经复潮时间均短于对照组(P<0.05)。治疗后,观察组患者均不需要清宫,对照组有4 例患者需要清宫,清宫率为8.00%,观察组清宫率低于对照组(P<0.05)。治疗后,2 组腹痛评分均较治疗前降低,观察组腹痛评分低于对照组,差异均有统计学意义(P<0.05)。观察组不良反应发生率为16.00%,低于对照组的34.00%(P<0.05)。结论:八珍益母胶囊联合屈螺酮炔雌醇片治疗药物流产后阴道出血,能够缩短阴道出血时间,减少清宫例数,用药安全性好。

    Abstract:

    Abstract: Objective: To observe the clinical effect of Bazhen Yimu capsules combined with drospirenone and ethinylestradiol tablets for vaginal bleeding after medical abortion. Methods: A total of 100 cases of patients undergoing medical abortion were selected as the study objects, and divided into the observation group and the control group according to the random number table method, 50 cases in each group. Both groups were given mifepristone combined with misoprostol tablets for medical abortion. The control group was given drospirenone and ethinylestradiol tablets after the discharge of gestational sac, and the observation group was additionally given Bazhen Yimu capsules based on the treatment of the control group. Both groups were treated for three weeks. After treatment, the time when the vaginal bleeding volume was more than menstrual volume, the vaginal bleeding duration, the time of menses recovery, the number of people undergoing curettage, and the incidence of abdominal pain and adverse reactions were recorded and compared between the two groups. Results:The time when the vaginal bleeding volume was more than menstrual volume, the vaginal bleeding duration and the time of menses recovery in the observation group were shorter than those in the control group(P<0.05). After treatment, there was no need for curettage in the observation group;in the control group, there were 4 cases of patients who needed curettage, and the curettage rate was 8.00%,the curettage rate in the observation group was lower than that in the control group(P<0.05). After treatment, the scores of abdominal pain in the two groups were decreased when compared with those before treatment(P<0.05), and the score in the observation group was lower than that in the control group(P<0.05). The incidence of adverse reactions was 16.00% in the observation group, lower than that of 34.00% in the control group(P<0.05). Conclusion: The therapy of Bazhen Yimu capsules combined with drospirenone and ethinylestradiol tablets in treating vaginal bleeding after medical abortion, which can shorten the vaginal bleeding time and reduce the cases of curettage, with good medication safety.

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施嗣.八珍益母胶囊联合屈螺酮炔雌醇片治疗药物流产后阴道出血临床研究[J].新中医,2020,52(15):119-121

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  • 在线发布日期: 2020-08-08
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