Abstract： Objective： To observe the clinical effect of Bazhen Yimu Capsules in adjuvant therapy of uterine adenomyosis. Methods：A total of 80 cases of patients with uterine adenomyosis of qi stagnation and blood stasis type were selected and divided into the control group and the observation group according to the random number table method， with 40 cases in each group. The control group was treated with Gestrinone and Diclofenac Sodium，and the observation group was additionally treated with Bazhen Yimu Capsules based on the treatment of the control group. The uterine volume， dysmenorrhea scores， traditional Chinese medicine syndrome scores，the levels of pain indexes including prostaglandin E2 (PGE2) and 5-hydroxytryptamine (5-HT) in serum before and after treatment，and clinical effects were compared between the two groups. Results： The total effective rate was 90.00% in the observation group， significantly higher than that of 72.50% in the control group， the difference being significant (P＜0.05). Before treatment， there was no significant difference being found in the comparison of the scores of abdominal pain and distension，pain remission after clots discharge，inhibited menstruation，vexation and irascibility， chest oppression， distending pain of the breasts， menses with purple clots， and scanty periods and the total scores between the two groups (P＞0.05). After treatment， the above syndrome scores and the total scores in the two groups were significantly decreased when compared with those before treatment (P＜0.05)，and the above syndrome scores and the total score in the observation group were lower than those in the control group (P＜0.05). Before treatment，there was no significant difference being found in the comparison of uterine volume and dysmenorrhea scores between the two groups (P＞ 0.05). After treatment， uterine volume and dysmenorrhea scores in the two groups were significantly decreased when compared with those before treatment (P＜0.05)， and the above two indexes in the observation group were lower than those in the control group (P＜0.05). Before treatment，there was no significant difference being found in the comparison of the levels of PGE2 and 5-HT in serum between the two groups (P＞0.05). After treatment， the levels of PEG2 and 5- HT in serum in the two groups were significantly decreased when compared with those before treatment (P＜0.05)，and the above two levels in the observation group were lower than those in the control group (P＜0.05). Conclusion： Bazhen Yimu Capsules in adjuvant therapy of uterine adenomyosis can significantly enhance clinical effects， decrease uterine volume， effectively reduce the levels of serum pain medium， and thus relieve dysmenorrhea symptoms.