目的：观察湿疡宁洗方熏洗坐浴联合外用湿毒膏治疗肛周湿疹的临床疗效。方法：选取88 例肛周湿疹患者，按随机数字表法分为观察组和对照组各44 例。对照组给予湿毒膏治疗，观察组在对照组基础上给予湿疡宁洗方熏洗坐浴治疗。评价2 组临床疗效，比较2 组临床症状评分、生活质量及复发率。结果：观察组总有效率为93.18%，高于对照组77.27%（P＜0.05）。治疗后，2 组湿疹面积、皮肤渗出液、瘙痒程度、皮损状态评分较治疗前降低（P＜0.05），且观察组各项评分均低于对照组（P＜0.05）。治疗后，2 组心理状态、生理功能、社会关系及物质生活评分较治疗前升高（P＜0.05），且观察组各项评分均高于对照组（P＜0.05）。观察组3 个月内复发率为6.82%，低于对照组的25.00%（P＜0.05）。结论：湿疡宁洗方熏洗坐浴联合湿毒膏外用治疗肛周湿疹临床疗效显著，可有效改善患者临床症状，提升生活质量，降低复发率。
Abstract：Objective：To observe the clinical effect of fumigation- washing sitz bath with Shiyangning Washing Prescription combined with external application of Shidu Ointment for perianal eczema. Methods： A total of 88 cases of patients with perianal eczema were divided into the observation group and the control group according to the random number table method，with 44 cases in each group. The control group was treated with Shidu Ointment ，and the observation group was additionally treated with fumigation-washing sitz bath with Shiyangning Washing Prescription based on the treatment of the control group. The clinical effects in the two groups were evaluated； the scores of clinical symptoms， the quality of life and the recurrence rates in the two groups were compared. Results： The total effective rate was 93.18% in the observation group，higher than that of 77.27% in the control group(P＜0.05). After treatment，the scores of eczema area， skin exudate， pruritus degree and skin lesion in the two groups were decreased when compared with those before treatment(P＜0.05)， and the above scores in the observation group were lower than those in the control group(P＜0.05). After treatment，the scores of mental state，physiological function，social relationship and material life in the two groups were increased when compared with those before treatment(P＜0.05)， and each score in the observation group was higher than that in the control group(P＜0.05). The recurrence rate within three months was 6.82% in the observation group，lower than that of 25.00% in the control group(P＜0.05). Conclusion： The therapy of fumigation- washing sitz bath with Shiyangning Washing Prescription combined with external application of Shidu Ointment for perianal eczema has a significant clinical effect， which can effectively improve the clinical symptoms of patients， improve their quality of life，and reduce the recurrence rate.