目的：观察壮骨活血汤辅助椎体后凸成形术治疗胸腰椎压缩性骨折的临床疗效。方法：选取胸腰椎压缩性骨折患者68 例，按随机数字表法分为对照组和研究组各34 例。对照组采用椎体后凸成形术（PKP）治疗，研究组在对照组基础上给予壮骨活血汤辅助治疗。评价2 组临床疗效，比较2 组治疗前后Cobb 角、椎体前缘丢失高度、疼痛程度及Barthel 指数。结果：研究组临床总有效率为94.12%，高于对照组76.47%（P＜0.05）。2 组治疗后Cobb 角、椎体前缘丢失高度均低于治疗前（P＜0.05）；研究组治疗后Cobb 角、椎体前缘丢失高度均低于对照组（P＜0.05）。2 组治疗后疼痛视觉模拟评分法（VAS） 评分较治疗前降低（P＜0.05），且研究组治疗后VAS 评分低于对照组（P＜0.05）。2 组治疗后Barthel 指数高于治疗前（P＜0.05），且研究组治疗后Barthel 指数高于对照组（P＜0.05）。结论：壮骨活血汤辅助椎体后凸成形术治疗胸腰椎压缩性骨折的疗效确切，可降低Cobb 角和椎体前缘丢失高度，缓解患者疼痛症状，提高日常生活能力。
Abstract：Objective：To observe the clinical effect of the therapy of Zhuanggu Huoxue Tang assisting percutaneous kyphoplasty on thoracolumbar vertebral compression fracture. Methods：A total of 68 patients with thoracolumbar vertebral compression fracture were selected and divided into the control group and the study group according to the random number table method，with 34 cases in each group. The control group was treated with percutaneous kyphoplasty(PKP)， and the study group was additionally given adjuvant treatment with Zhuanggu Huoxue Tang based on the treatment of the control group. The clinical effects in the two groups were evaluated. Before and after treatment， the Cobb angles， anterior vertebral height loss，degree of pain and scores of Barthel index were compared between the two groups. Results：The total clinical effective rate was 94.12% in the study group，higher than that of 76.47% in the control group (P＜0.05). After treatment，the Cobb angles and anterior vertebral height loss in the two groups were lower than those before treatment(P＜0.05)；after treatment，the Cobb angles and anterior vertebral height loss in the study group were lower than those in the control group(P＜0.05). After treatment， the scores of Visual Analogue Scale(VAS) for pain were decreased when compared with those before treatment(P＜ 0.05)， and the score of VAS in the study group was lower than that in the control group(P＜0.05). After treatment，the scores of Barthel index were higher than those before treatment(P＜0.05)，and the above score in the study group was higher than that in the control group(P＜0.05). Conclusion： The therapy of Zhuanggu Huoxue Tang assisting PKP has a definite curative effect on thoracolumbar vertebral compression fracture，which can reduce the Cobb angles and anterior vertebral height loss，relieve the pain of patients， and improve the ability of daily living.