小儿肺热咳喘颗粒联合西医常规治疗小儿风热犯肺证支气管炎临床研究
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Clinical Study on Xiao'er Feire Kechuan Granules Combined with Routine Western Medicine for Children with Bronchitis with Wind-Heat Invading the Lung Syndrome
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    摘要:

    目的:观察小儿肺热咳喘颗粒联合西医常规治疗小儿风热犯肺证支气管炎的临床疗效及对血清C-反应蛋白(CRP)、降钙素原(PCT) 水平的影响。方法:选取支气管炎患儿70 例,按随机数字表法分为对照组和观察组各35 例。对照组予西医常规治疗;观察组在对照组的基础上予小儿肺热咳喘颗粒治疗。2 组均连续治疗7 d,比较2 组症状体征消失时间、血清PCT、CRP 水平及临床疗效。结果:观察组总有效率为100%,对照组为82.86%,2 组比较,差异有统计学意义(P<0.05)。治疗后,观察组退热、咳嗽、肺部啰音的消失时间均短于对照组,差异有统计学意义(P<0.05)。治疗前,2 组血清PCT、CRP水平比较,差异无统计学意义(P>0.05)。治疗后,2 组血清PCT、CRP 水平均较治疗前明显降低(P<0.05),且观察组血清PCT、CRP 水平明显低于对照组(P<0.05)。结论:在西医常规治疗的基础上,联合小儿肺热咳喘颗粒治疗小儿风热犯肺证支气管炎疗效显著,能有效抑制患儿机体炎症反应,加速病情改善。

    Abstract:

    Abstract: Objective: To observe the clinical effect of Xiao'er Feire Kechuan granules combined with routine western medicine for children with bronchitis with wind-heat invading the lung syndrome and its effect on levels of C-reactive protein (CRP) and procalcitonin(PCT) in serum. Methods:A total of 70 cases of children with bronchitis were selected and divided into the control group and the observation group according to the random number table method,with 35 cases in each group. The control group was given routine treatment of western medicine, and the observation group was treated with Xiao'er Feire Kechuan granules based on the treatment of the control group. Both groups were treated for seven days. The disappearance time of symptoms and signs,the levels of PCT and CRP in serum and the clinical effects in the two groups were compared. Results:The total effective rate was 100% in the observation group and 82.86% in the control group,the difference being significant(P<0.05). After treatment,the disappearance time of fever,cough and pulmonary rales in the observation group was shorter than that in the control group, the difference being significant(P<0.05). Before treatment, there was no significant difference being found in the comparison of levels of PCT and CRP in serum between the two groups(P>0.05). After treatment,the levels of PCT and CRP in serum in the two groups were significantly decreased when compared with those before treatment(P<0.05),and the levels of PCT and CRP in serum in the observation group were significantly lower than those in the control group(P<0.05). Conclusion: Based on routine treatment of western medicine, the additional application of Xiao'er Feire Kechuan granules has a significant curative effect in treating children with bronchitis with windheat invading the lung syndrome, which can effectively inhibit inflammatory responses in the body of children, and accelerate the improvement of disease.

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田华,姚晓波.小儿肺热咳喘颗粒联合西医常规治疗小儿风热犯肺证支气管炎临床研究[J].新中医,2022,54(12):151-154

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  • 在线发布日期: 2022-06-22
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