血府逐瘀胶囊联合右佐匹克隆片治疗脑卒中后失眠瘀血内阻证临床研究
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R255.2;R256.23

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Clinical Study on Xuefu Zhuyu Capsules Combined with Dexzopiclone Tablets for Insomnia After Stroke with Internal Obstruction of Blood Stasis Syndrome
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    摘要:

    目的:观察血府逐瘀胶囊联合右佐匹克隆片治疗脑卒中后失眠瘀血内阻证的临床疗效。方法:选取102 例脑卒中后失眠瘀血内阻证患者,按随机数字表法分为对照组和观察组各51 例。对照组给予右佐匹克隆片治疗,观察组在对照组基础上给予血府逐瘀胶囊治疗,2 组均治疗2 个月。比较2 组治疗前后匹兹堡睡眠质量指数(PSQI)、Barthel 指数评分;比较2 组临床疗效。结果:治疗后,2 组入睡时间、睡眠效率、睡眠时间、睡眠障碍、日间功能评分均较治疗前降低(P<0.05),观察组上述各项评分均低于对照组(P<0.05)。治疗后,2 组Barthel 指数评分均较治疗前升高(P<0.05),观察组Barthel 指数评分高于对照组(P<0.05)。观察组总有效率96.08%,高于对照组80.39%(P<0.05)。结论:血府逐瘀胶囊联合右佐匹克隆片治疗脑卒中后失眠瘀血内阻证疗效较好,可改善患者的睡眠质量,提高其日常生活能力。

    Abstract:

    Abstract: Objective: To observe the clinical effect of Xuefu Zhuyu capsules combined with dexzopiclone tablets for insomnia after stroke with internal obstruction of blood stasis syndrome. Methods: A total of 102 cases of patients with insomnia after stroke with internal obstruction of blood stasis syndrome were selected and divided into the control group and the observation group according to the random number table method,with 51 cases in each group. The control group was treated with dexzopiclone tablets,and the observation group was additionally treated with Xuefu Zhuyu capsules based on the treatment of the control group. Both groups were treated for two months. The scores of Pittsburgh Sleep Quality Index (PSQI) and Barthel index before and after treatment as well as the clinical effects in the two groups were compared. Results: After treatment,time for falling asleep,sleep efficiency,sleep duration,sleep disorders and daytime function scores in the two groups were decreased when compared with those before treatment(P<0.05),and the above scores in the observation group were lower than those in the control group(P<0.05). After treatment, Barthel index scores in the two groups were increased when compared with those before treatment(P<0.05),and the Barthel index scores in the observation group was higher than that in the control group(P<0.05). The total effective rate was 96.08% in the observation group,higher than that of 80.39% in the control group(P<0.05). Conclusion: The therapy of Xuefu Zhuyu capsules combined with dexzopiclone tablets for insomnia after stroke with internal obstruction of blood stasis syndrome has a good curative effect, which can improve the sleep quality of patients and enhance their activities of daily living.

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郑云华,詹根龙,刘烨.血府逐瘀胶囊联合右佐匹克隆片治疗脑卒中后失眠瘀血内阻证临床研究[J].新中医,2022,54(10):55-57

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  • 在线发布日期: 2022-05-24
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