挂金灯汤治疗慢性咽炎肝郁化火证临床研究
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R766.14

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山西省科技厅攻关项目(201806D211003)


Clinical Study on Guajindeng Tang for Chronic Pharyngitis with Syndrome of Depressed Liver Qi Transforming into Fire
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    摘要:

    目的:观察挂金灯汤治疗肝郁化火型慢性咽炎的临床疗效。方法:将135 例肝郁化火型慢性咽炎患者纳入研究,按照随机数字表法分为挂金灯汤组、布地奈德组及蓝芩口服液组各45 例,挂金灯汤组予挂金灯汤治疗,布地奈德组予布地奈德雾化治疗,蓝芩口服液组予蓝芩口服液治疗。3 组均治疗2 周,随访3 个月。比较3 组治疗前后的症状积分、治疗后的临床疗效及随访3 个月内的复发率。结果:治疗2 周后,3 组症状积分均较治疗前下降(P<0.05);3 组症状积分比较,差异有统计学意义(P<0.05);挂金灯汤组的症状积分低于布地奈德组及蓝芩口服液组(P<0.05),布地奈德组的症状积分与蓝芩口服液组相比,差异无统计学意义(P>0.05)。随访3 个月内,布地奈德组的复发率高于挂金灯组(P<0.05)。随访3 个月,挂金灯汤组的临床疗效总有效率高于布地奈德组及蓝芩口服液组(P<0.05),布地奈德组的总有效率与蓝芩口服液组比较,差异均无统计学意义(P>0.05)。结论:挂金灯汤可改善慢性咽炎患者的临床症状,减少慢性咽炎复发。

    Abstract:

    Abstract: Objective: To observe the clinical effect of Guajindeng tang on chronic pharyngitis with syndrome of depressed liver qi transforming into fire. Methods: A total of 135 patients with chronic pharyngitis with type of depressed liver qi transfoming in fire were selected and divided into the Guajindeng group,the budesonide group and the Lanqin oral liquid group according to the random number table method,with 45 cases in each group. The Guagjindeng tang group was treated with Guajindeng tang, the budesonide group was treated with aerosol therapy of budesonid, and the Lanqin oral liquid group was treated with Lanqin oral liquid. Three groups were treated for two weeks and followed up for three months. Before and after treatment,the symptom scores,clinical effects and recurrence rates within three months of follow-up in the three groups were compared. Results: After two weeks of treatment, the symptom scores in the three groups were decreased when compared with those before treatment(P<0.05);the comparisons of symptom scores in the three groups showed significant difference(P<0.05);the symptom score in the Guajindeng tang group was lower than that in the Lanqin oral liquid group and the budesonide group respectively(P<0.05),and there was no significant difference being found in the comparison of symptom scores between the budesonide group and the Lanqin oral liquid group(P>0.05). During three months of follow-up,the recurrence rates in the budesonide group was higher than that in the Guajindeng tang group(P<0.05). After three months of follow-up,the total effective rate in the Guajindeng tang group was higher than that in the budesonide group and the Lanqin oral liquid group respectively(P<0.05), and there were no significant differences being found in the comparison of total effective rates between the the budesonide group and the Lanqin oral liquid group(P>0.05). Conclusion: The therapy of Guajindeng tang can improve the clinical symptoms of patients with chronic pharyngitis and reduce the recurrence rate of chronic pharyngitis.

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薛晓明,李豪,孟丽红,周波波,尚芳,张莉,陈旭,张罗丹,孙耀琴.挂金灯汤治疗慢性咽炎肝郁化火证临床研究[J].新中医,2022,54(2):135-138

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  • 在线发布日期: 2022-01-22
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