肺炎汤与穴位敷贴联合西药治疗儿童痰热壅肺型肺炎支原体肺炎临床研究
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R725.6

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Clinical Study on Feiyan Tang and Point Application Combined with Western Medicine for Children with Mycoplasma Pneumoniae Pneumonia of Phlegm-Heat Obstructing the Lung Type
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    摘要:

    目的:观察在常规西药基础上加用肺炎汤与穴位敷贴治疗痰热壅肺型肺炎支原体肺炎(MPP) 患儿的临床效果。方法:选取102 例痰热壅肺型MPP 患儿,采用随机数字表法分为观察组和对照组各51 例。2 组均给予抗感染、止咳、平喘等常规治疗,观察组加予肺炎汤联合穴位敷贴治疗。2 组均治疗2 周。观察记录2 周内2 组患儿的咳嗽、发热、肺部啰音持续时间。治疗前后检测血清免疫球蛋白(Ig) A、IgM、白细胞介素-10(IL-10)、自然杀伤(NK) 细胞水平。记录治疗2 周内患儿的不良反应发生情况。比较2 组的治疗效果。结果:治疗后,观察组的整体疗效优于对照组,差异有统计学意义(P<0.05)。观察组的咳嗽、发热、肺部啰音持续时间均短于对照组(P<0.01)。2 组IgA、IgM 水平与治疗前相比均下降(P<0.01)。观察组IgA、IgM水平均低于对照组(P<0.05,P<0.01)。2 组IL-10 水平均较治疗前下降,NK 细胞水平均较治疗前上升,差异均有统计学意义(P<0.01)。观察组IL-10 水平低于对照组,NK 细胞水平高于对照组,差异均有统计学意义(P<0.05,P<0.01)。治疗过程中,2 组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:在常规西药基础上加用肺炎汤联合穴位敷贴治疗痰热壅肺型MPP 患儿能更加有效地缓解临床症状,改善患儿的免疫功能,对提高临床疗效具有积极作用。

    Abstract:

    Abstract:Objective:To observe the clinical effect of the therapy of Feiyan tang and point application based on western medicine on children with mycoplasma pneumoniae pneumonia(MPP) of phlegm-heat obstructing the lung type. Methods:A total of 102 children with MPP of phlegm-heat obstructing the lung type were selected and divided into the observation group and the control group by random number table method,with 51 cases in each group. Both groups were given conventional treatment such as anti-infection,relieving cough and relieving asthma,while the observation group was additionally treated with Feiyan tang and point application. Both groups were treated for two weeks. The duration of cough,fever and lung rales in the two groups were observed and recorded within two weeks. The levels of serum immunoglobulins(IgA and IgM), interleukin-10(IL-10) and natural killer(NK) cell were detected before and after treatment. The incidence of adverse reactions within two weeks of treatment was recorded. The therapeutic effects in the two groups were compared. Results: After treatment, the overall effect in the observation group was better than that in the control group, the difference being significant(P<0.05). The duration of cough,fever and lung rales in the observation group was shorter than that in the control group(P<0.01). The levels of IgA and IgM in both groups were decreased when compared with those before treatment(P< 0.01). The levels of IgA and IgM in the observation group were lower than those in the control group(P<0.05,P<0.01). The levels of IL- 10 in both groups were decreased when compared with those before treatment, and the NK cell levels were increased,differences being significant(P<0.01). The IL-10 level in the observation group was lower than that in the control group,and the NK cell level was higher,differences being significant(P<0.05,P<0.01). During treatment,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05). Conclusion: On the basis of conventional western medicine treatment,the additional application of Feiyan tang and point application in the treatment of children with MPP of phlegm-heat obstructing the lung type can alleviate clinical symptoms more effectively and improve the immune function,which plays a positive role in improving clinical effect.

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袁方.肺炎汤与穴位敷贴联合西药治疗儿童痰热壅肺型肺炎支原体肺炎临床研究[J].新中医,2022,54(2):126-130

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  • 在线发布日期: 2022-01-22
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