益气养阴利水方联合常规西药治疗老年慢性心力衰竭临床研究
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Clinical Study on Yiqi Yangyin Lishui Prescription Combined with Routine Western Medicine for Elderly Patients with Chronic Heart Failure
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    摘要:

    目的:观察益气养阴利水方联合常规西药治疗老年慢性心力衰竭(CHF) 的疗效及对患者心功能、血流动力学参数的影响。方法:选取老年CHF 患者123 例,根据掷币法分为2 组,对照组61 例,观察组62 例。对照组给予常规西药治疗,观察组在对照组基础上联用益气养阴利水方治疗,持续治疗8 周。比较2 组治疗前后心功能指标、血流动力学指标水平变化,并评价2 组临床疗效。结果:治疗后,2 组左室收缩末期内径(LVESD)、左室舒张末期内径(LVEDD) 及脑利钠肽(BNP) 水平明显降低,左室射血分数(LVEF) 明显升高,且观察组优于对照组,差异有统计学意义(P<0.05)。治疗后,2 组心输出量(CO)、心脏指数(CI)、每搏输出量(SV) 较治疗前明显升高,且观察组CO、CI、SV 高于对照组,血管阻力(SVR) 及再入院率低于对照组,差异均有统计学意义(P<0.05)。观察组总有效率为93.55%,高于对照组70.49%,差异有统计学意义(P<0.05)。结论:益气养阴利水方联合常规西药治疗老年CHF 患者疗效显著,能明显改善患者心功能及血流动力学参数,降低患者再入院率。

    Abstract:

    Abstract: Objective: To observe the effect of the therapy of Yiqi Yangyin Lishui prescription combined with routine western medicine on elderly patients with chronic heart failure(CHF) and its effect on the heart function and hemodynamic parameters of patients. Methods:A total of 123 elderly patients with CHF were selected and divided into the control group group and the observation group according to the coin tossing method, with 61 cases and 62 cases in each group respectively. The control group was treated with routine western medicine, and the observation group was additionally treated with Yiqi Yangyin Lishui prescription based on the treatment of the control group. Both groups were treated for eight weeks. The changes of levels of indexes of the heart function and hemodynamics before and after treatment in the two groups were compared and the clinical effects were evaluated. Results:After treatment,the levels of left ventricular endsystolic diameter(LVESD),left ventricular end diastolic diameter(LVEDD) and brain natriuretic peptide(BNP) in the two groups were significantly decreased,and the left ventricular ejection fraction(LVEF) was significantly increased,and the above levels in the observation group were better than those in the control group, the difference being significant(P<0.05). After treatment, the levels of cardiac output(CO), cardiac index(CI) and stroke volume(SV) in the two groups were significantly increased when compared with those before treatment,and the above levels in the observation group were higher than those in the control group,and the level of systematic vascular resistance(SVR) and readmission rate were lower than those in the control group,differences being significant(P<0.05). The total effective rate was 93.55% in the observation group,higher than that of 70.49% in the control group,the difference being significant(P<0.05). Conclusion:The therapy of Yiqi Yangyin Lishui prescription combined with routine western medicine for elderly patients with CHF has a significant curative effect, which can significantly improve the heart function and hemodynamic indexes of patients,and reduce the readmission rate.

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李伟,王玉晓.益气养阴利水方联合常规西药治疗老年慢性心力衰竭临床研究[J].新中医,2021,53(23):75-79

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  • 在线发布日期: 2021-12-10
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