麝香保心丸联合单硝酸异山梨酯缓释片治疗冠心病心绞痛临床研究
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Clinical Study on Shexiang Baoxin Pills Combined with Isosorbide Mononitrate Sustained-Release Tablets for Angina Pectoris of Coronary Heart Disease
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    摘要:

    目的:观察麝香保心丸联合单硝酸异山梨酯缓释片治疗冠心病心绞痛(AP)患者的临床疗效。方法:将 78 例 AP 患者分为对照组和治疗组,各 39 例。对照组口服单硝酸异山梨酯缓释片治疗,治疗组在对照组用药基础上给予麝香保心丸治疗。观察 2 组心电图疗效、治疗前后心绞痛发作持续时间、左室射血分数、心排血量及不良反应情况。结果:治疗后对照组心电图总有效率为 87.18%,治疗组为 97.44%,2 组比较,差异有统计学意义 (P<0.05)。与同组治疗前比较,治疗后 2 组心绞痛持续时间均下降 (P<0.05),且治疗组短于对照组 (P<0.05);与同组治疗前比较,治疗后 2 组左室射血分数、心排血量上升 (P< 0.05),且治疗组高于对照组(P<0.05);2 组患者均未出现不良反应。结论:麝香保心丸治疗 AP 临疗效显著,能有效改善患者心功能且安全性高。

    Abstract:

    Abstract: Objective: To observe the clinical effect of Shexiang Baoxin pills combined with isosorbide mononitrate sustained-release tablets for angina pectoris(AP) of coronary heart disease. Methods:A total of 78 cases of AP patients were divided into the control group and the treatment group, 39 cases in each group. The control group was given oral administration of isosorbide mononitrate sustained- release tablets,and the treatment group was additionally treated with Shexiang Baoxin pills based on the treatment of the control group. The electro cardiogram efficacy was observed in the two groups. Before and after treatment,the duration of angina pectoris,the score of left ventricular ejection fraction,cardiac output volume and adverse reactions were observed in the two groups. Results:The total effective rate of electrocardiogram was 87.18% in the control group, and 97.44% in the treatment group, the difference being significant(P<0.05). When compared with those in the same group before treatment,the duration of angina pectoris in the two groups after treatment was decreased(P<0.05),and the duration in the treatment group was shorter than that in the control group(P<0.05). When compared with those in the same group before treatment,the score of left ventricular ejection fraction and cardiac output volume in the two groups after treatment were increased(P<0.05),and the two indexes in the treatment group were higher than those in the control group(P<0.05). No adverse reactions occurred in the two groups. Conclusion:Shexiang Baoxin pills has a significant clinical effect on AP,and can effectively improve the heart function with high safety.

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诸葛泽.麝香保心丸联合单硝酸异山梨酯缓释片治疗冠心病心绞痛临床研究[J].新中医,2021,53(7):58-60

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  • 在线发布日期: 2021-04-08
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