目的：探讨半夏白术天麻汤联合盐酸多奈哌齐对阿尔茨海默病患者副反应量表（TESS） 评分的影响。方法：将阿尔茨海默病患者120 例根据治疗方法的不同随机分为2 组各60 例，对照组使用半夏白术天麻汤治疗，研究组使用半夏白术天麻汤联合盐酸多奈哌齐治疗。对比2 组治疗效果、生活质量（QOL） 评分、并发症发生情况以及TESS 和生活能力（ADL） 评分情况。结果：研究组的总有效率为96.7%，明显高于对照组的88.3%（P＜0.05）。2 组治疗前各项QOL 评分比较，差异无统计学意义（P＞0.05）。治疗后，2 组各项QOL 评分较前改善（P＜0.05），研究组QOL 评分高于对照组（P＜0.05）。研究组并发症发生率低于对照组（P＜0.05）。治疗前，2 组TESS、ADL 评分比较，差异无统计学意义（P＞0.05）。治疗后，2 组TESS、ADL 评分较前改善（P＜0.05）。研究组TESS 评分低于对照组（P＜0.05），而ADL 评分高于对照组（P＜0.05）。结论：半夏白术天麻汤联合盐酸多奈哌齐治疗阿尔茨海默病，可提高患者的生活水平，降低并发症产生率，可改善精神行为，不良反应低。
Abstract： Objective： To discuss the effect of Banxia Baizhu Tianma tang combined with donepezil hydrochloride on Treatment Emergent Symptom Scale(TESS) scores in patients with Alzheimer disease. Methods： A total of 120 cases of patients with Alzheimer disease were randomly divided into two groups according to different treatment methods，60 cases in each group. The control group was treated with Banxia Baizhu Tianma tang，and the study group was treated with Banxia Baizhu Tianma tang combined with donepezil hydrochloride. The clinical effect， quality of life(QOL) scores， incidence of complications and scores of TESS and activities of daily living(ADL) in the two groups were compared. Results： The total effective rate was 96.7% in the study group， significantly higher than that of 88.3% in the control group(P＜0.05). Before treatment，there was no significant difference being found in the comparison of QOL scores between the two groups(P＞ 0.05). After treatment，the QOL scores in the two groups were improved when compared with those before treatment(P＜ 0.05)，and the score in the study group was higher than that in the control group(P＜0.05). The incidence of complications in the study group was lower than that in the control group(P＜0.05). Before treatment， there was no significant difference being found in the comparisons of scores of TESS and ADL between the two groups(P＞0.05). After treatment，the scores of TESS and ADL in the two groups were improved when compared with those before treatment(P＜0.05). In the study group， the TESS score was lower than that in the control group(P＜0.05)， and the ADL score was higher(P＜0.05). Conclusion： Banxia Baizhu Tianma tang combined with donepezil hydrochloride in treating Alzheimer disease can improve living standard， reduce incidence of complications and improve mental behavior with low adverse reactions.