疏肝解郁胶囊联合理疗在焦虑抑郁患者中的应用及对患者应激反应的影响
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Application of Shugan Jieyu Capsules Combined with Physical Therapy on Patients with Anxiety and Depression and Its Effect on Stress Response
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    摘要:

    目的:探讨疏肝解郁胶囊联合理疗在焦虑抑郁患者中的应用及对患者应激反应的影响。方法:将 104 例焦虑抑郁患者应用信封法分为研究组和对照组各 52 例。对照组采取疏肝解郁胶囊治疗,研究组在对照组基础上联合理疗治疗,2 组疗程均为 4 个月。观察比较 2 组应激反应激素水平、焦虑抑郁情绪评分以及临床疗效。结果:研究组临床总有效率(94.2%)高于对照组 (84.6%),差异有统计学意义 (χ2=7.154,P<0.05)。治疗前,2 组促肾上腺皮质激素 (ATCH)、促肾上腺激素释放激素(CRH)、皮质醇 (CORT)、生长素 (HGH) 水平比较,差异无统计学意义 (P>0.05)。治疗后,2 组 ACTH、CRH、CORT 水平较治疗前降低,HGH 水平较治疗前升高 (P<0.05);且研究组 ACTH、CRH、CORT 水平低于对照组,HGH 水平高于对照组(P<0.05)。治疗前,2 组汉密尔顿焦虑量表(HAMA-14)评分及汉密尔顿抑郁量表(HAMD-17)评分比较,差异无统计学意义(P>0.05)。治疗后,2 组 HAMA-14 评分及 HAMD-17 评分较治疗前降低,且研究组 HAMA-14 评分及 HAMD-17 评分低于对照组,差异均有统计学意义(P<0.05)。结论:疏肝解郁胶囊联合理疗治疗焦虑抑郁患者效果确切,可调解应激反应指标水平及改善患者焦虑抑郁评分。

    Abstract:

    Abstract:Objective:To discuss the application of Shugan Jieyu capsules combined with physical therapy on patients with anxiety and depression and its effect on their stress response. Methods:A total of 104 cases of patients with anxiety and depression were divided into the study group and the control group by sealed envelope method,52 cases in each group. The control group was treated with Shugan Jieyu capsules,and the study group was additionally treated with physical therapy based on the treatment of the control group. Both groups were treated for four months. The levels of stress hormone,the scores of anxiety and depression and clinical effect were observed and compared between the two groups. Results:The total clinical effective rate was 94.2% in the study group,higher than that of 84.6% in the control group,the difference being significant(χ2=7.154,P<0.05). Before treatment,compared the levels of adrenocorticotropic hormone(ATCH),corticotropin releasing hormone(CRH), cortisol(CORT) and human growth hormone(HGH) between the two groups, there was no significance in the difference(P>0.05). After treatment, the levels of ACTH, CRH and CORT in the two groups were decreased when compared with those before treatment, and the levels of HGH were increased(P<0.05); the levels of ACTH,CRH and CORT in the study group were lower than those in the control group,and the level of HGH was higher (P<0.05). Before treatment,compared the scores of Hamilton Anxiety Scale(HAMA- 14) as well as Hamilton Depression Scale(HAMD-17) between the two groups,there was no significance in the difference(P>0.05). After treatment,the scores of HAMA-14 and HAMD-17 in the two groups were decreased when compared with those before treatment,and the two scores in the study group were lower than those in the control group,differences being significant(P<0.05). Conclusion: The therapy of Shugan Jieyu capsules combined with physical therapy has defined effect in treating patients with anxiety and depression,which can regulate the levels of stress response indexes and improve the scores of anxiety and depression.

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李亚楠,魏英杰,吕娟,李鹏燕,赵杰,王润青.疏肝解郁胶囊联合理疗在焦虑抑郁患者中的应用及对患者应激反应的影响[J].新中医,2020,52(23):47-50

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  • 在线发布日期: 2020-12-09
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