目的：观察小儿豉翘清热颗粒治疗胃肠型感冒风热犯表夹滞证的临床疗效。方法：将110 例患儿按照随机数字表法分成对照组和观察组各55 例。对照组予清开灵颗粒联合枯草杆菌二联活菌颗粒治疗，观察组予小儿豉翘清热颗粒治疗。2 组疗程均为3 d。若体温≥38.5 ℃，给予布洛芬颗粒温水冲服。记录退热起效时间与解热时间，计算2 组的退热率和解热率；治疗前后评定风热犯表夹滞证评分。结果：治疗后，观察组疗效优于对照组（P＜0.05）。观察组退热起效时间和解热时间均较对照组加快（P＜0.01）。治疗第1 天，观察组退热率90.91%，高于对照组的74.55%，差异有统计学意义（P＜0.05）。治疗第2 天和第3 天，2 组退热率比较，差异均无统计学意义（P＞0.05）。治疗1～3 d，观察组的解热率均高于对照组（P＜0.05）。2 组鼻咽部症状、全身症状、胃肠道症状的评分及总分均较治疗前下降（P＜0.01），观察组3 项症状评分及总分均低于对照组（P＜0.01）。结论：应用小儿豉翘清热颗粒治疗胃肠型感冒风热犯表夹滞证可快速起退热效果，有显著的解热疗效，缩短了发热病程，并且对鼻咽部症状、全身症状和胃肠道症状均有显著的减轻作用。
Abstract： Objective： To observe the clinical effect of Xiao'er Chiqiao Qingre granules for gastrointestinal cold with exterior heat with food retention syndrome. Methods：A total of 110 cases of children were divided into the control group and the observation group according to the random number table method，55 cases in each group. The control group was treated with Qingkailing granules combined with enterococcus faecium granules，and the observation group was treated with Xiao'er Chiqiao Qingre granules. Both groups were treated for three days. If the body temperature was equal to or over 38.5 ℃，the oral administration of ibuprofen granules was taken after mixing with warm water. The onset time of defervesce and the antipyretic time were recorded. The defervesce rate and antipyretic rate in the two groups were counted. Before and after treatment，the scores of exterior heat with food retention syndrome were evaluated. Results：After treatment，the curative effect in the observation group was better than that in the control group(P＜0.05). The onset time of defervesce and the antipyretic time in the observation group were shortened when compared with those in the control group(P＜0.01). On the first day of treatment，the defervesce rate was 90.91% in the observation group，higher than that of 74.55% in the control group， the difference being significant(P＜0.05). On the second and third day of treatment respectively， there was no significant difference being found in the comparison of defervesce rates between the two groups(P＞0.05). After treatment for one to three days，the antipyretic rates in the observation group were all higher than those in the control group(P＜0.05). The scores of symptoms in the nose and pharynx，general symptoms and gastrointestinal symptoms as well as the total scores in the two groups were decreased when compared with those before treatment(P＜0.01)，the above scores in the observation group were all lower than those in the control group(P＜0.01). Conclusion：The application of Xiao'er Chiqiao Qingre granules for gastrointestinal cold with exterior heat with food retention syndrome can quickly play the role of defervesce， have significant antipyretic effect， shorten the course of fever， and significantly reduce the nasopharynx symptoms， systemic symptoms and gastrointestinal symptoms.