三阴性乳腺癌（TNBC） 是一类高危乳腺癌，易复发转移，预后差，是目前乳腺癌研究领域的热点和难点。尽管已有大量关于TNBC 分子机制的研究，相关药物也已用于临床，但存在费用昂贵、患者获益不大的问题。口服化疗药物作为术后预防复发转移的方法因有毒副作用，临床应用受到限制。中药作为预防TNBC 术后复发转移的手段有一定的优势，其效果和机制值得系统研究。回顾近年来中药内服预防TNBC 术后复发转移的临床对照研究，并对中成药、中药单体、中药复方等用于TNBC 的实验研究进行综述，以探讨中药预防TNBC 术后复发转移的作用及机制，利于进一步开展有针对性的相关研究。
Abstract：Triple negative breast cancer(TNBC) is a high-risk breast cancer and is apt to recur and metastasize with poor prognosis， which is now a hot and difficult topic in the field of breast cancer research. Although there have been a lot of studies on the molecular mechanism of TNBC and related drugs have been used in clinical practice，there are problems of high cost and little effect for patients. As a method to prevent postoperative recurrence and metastasis，oral administration of chemotherapeutic drugs is limited in clinical application due to its side effect. As a means to prevent postoperative recurrence and metastasis of TNBC， Chinese herbal medicine has certain advantages， and its effect and mechanism are worthy of systematic study. The clinical control studies on the prevention of postoperative recurrence and metastasis of TNBC by oral administration of Chinese herbal medicine in recent years was reviewed， and the experimental studies of Chinese patent medicine，Chinese medicine monomers and Chinese herbal compounds used for TNBC were summarized，so as to explore the effect and mechanism of Chinese herbal medicine in preventing postoperative recurrence and metastasis of TNBC，which is conducive to further well-directed research.