Objective：To observe the clinical effect of bone-setting manipulation in Chinese medicine combined with Tianma Gouteng yin for cervical spondylosis of vertebral artery type.M e th o d s：Divided 104 cases of patients with cervical spondylosis of vertebral artery type into the control group and the observation group randomly，52 cases in each group.Both groupsreceived Tianma Gouteng yin for treatment，whilethe observation group additionally received bone-setting manipulation in Chinese medicine.Compared the clinical effect in both groups，analyzed the changes of hemodynamic parameters before and after treatment，and statistically analyzed the occurrence of adverse reactions.R e s u lts：The total effective rate was 94.23%in the observation group and 78.85%in the control group，difference being significant(P＜0.05).After treatment，peak systolic velocity(PSV)and temporal mean flow velocity(TMFV)in both groups were both higher than those before treatment(P ＜ 0.05)，and pulsatility index(PI)and resistance index(RI)were both lower than those before treatment(P ＜ 0.05)；PSV and TMFV in the observation group were both higher than those in the control group(P ＜ 0.05)，and PI and RI were both lower than those in the control group(P＜0.05).During the treatment for both groups，there were no adverse reactions.Conclusion：Bone-setting manipulation in Chinese medicine combined with Tianma Gouteng yin for cervical spondylosis of vertebral artery type can effectively improve the symptoms and hemodynamic parameters in patients，and its clinical effect is better than that of the simple application of Tianma Gouteng yin for treatment.