益肾泄浊汤联合西药和血液透析治疗尿毒症临床研究
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Clinical Study on Yishen Xiezhuo Tang Combined with Western Medicine and Hemodi⁃ alysis for Uremia
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    摘要:

    目的:观察益肾泄浊汤联合西药和血液透析治疗尿毒症的临床疗效。方法:选取100 例尿毒症患者,按随机数字表法分为对照组和观察组,每组50 例。对照组给予西药和血液透析治疗,观察组在对照组基础上给予益肾泄浊汤治疗,2 组均连续治疗4 周。对比2 组症状积分、临床疗效、肾功能指标及营养学指标。结果:治疗后,观察组面色晦暗、倦怠乏力、食少纳呆、便溏浮肿积分均低于对照组(P<0.05)。观察组总有效率为96.00%,高于对照组的84.00%(P<0.05)。治疗后,观察组血尿素氮(BUN)、血肌酐(SCr) 及24 h 尿蛋白定量水平均低于对照组(P<0.05),内生肌酐清除率(CCr) 水平高于对照组(P<0.05)。治疗后,观察组血浆白蛋白、血浆前白蛋白、转铁蛋白及血红蛋白水平均高于对照组(P<0.05)。结论:益肾泄浊汤联合西药和血液透析治疗尿毒症,可有效改善患者的临床症状、肾功能及营养状况。

    Abstract:

    Abstract: Objective: To observe the clinical effect of Yishen Xiezhuo tang combined with western medicine and hemodialysis for uremia. Methods:A total of 100 cases of patients with uremia were selected and divided into the control group and the observation group according to the random number table method,50 cases in each group. The control group was given western medicine and hemodialysis,and the observation group was additionally treated with Yishen Xiezhuo tang based on the treatment of the control group. Both groups were continuously treated for four weeks. The symptom scores, clinical effect,the kidney function indexes and nutritional indexes were compared between the two groups. Results:After treatment, the scores of dim complexion, lassitude and lack of strength, lack of appetite and torpid intake, as well as sloppy stool and edema in the observation group were all lower than those in the control group(P<0.05). The total effective rate was 96.00% in the observation group,higher than that of 84.00% in the control group(P<0.05). After treatment,the levels of blood urea nitrogen(BUN),serum creatinine(SCr) and 24 h urine protein quantification in the observation group were lower than those in the control group(P<0.05), and the level of creatinine clearance rate(CCr) was higher than that in the control group(P<0.05). After treatment, the levels of albumin, prealbumin, transferrin and hemoglobin in serum in the observation groups were higher than those in the control group(P<0.05). Conclusion: The therapy of Yishen Xiezhuo tang combined with western medicine and hemodialysis in treating uremia, can effectively improve the clinical symptoms, the kidney function and nutritional status.

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谢凤娇,李元敏,朱炜丹.益肾泄浊汤联合西药和血液透析治疗尿毒症临床研究[J].新中医,2020,52(16):77-79

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  • 在线发布日期: 2020-08-19
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