当归四逆汤加减熏洗联合益脑增智针法治疗小儿脑瘫临床研究
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Clinical Study on Fuming-Washing with Modified Danggui Sini Tang Combined with Yinao Zengzhi Needling Method for Child Cerebral Palsy
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    摘要:

    目的:观察当归四逆汤加减熏洗联合益脑增智针法治疗小儿脑瘫的临床疗效。方法:选取116 例脑瘫患儿,按随机数字表法分为对照组和治疗组各58 例。对照组给予益脑增智针法治疗,治疗组在对照组基础上联合当归四逆汤加减熏洗治疗,每周治疗5 次,2 组均持续治疗12 周。比较2 组临床疗效,测试患儿治疗前后的精细运动情况,比较2 组血清炎症因子及胰岛素样生长因子-1(IGF-1) 水平,记录不良反应发生情况。结果:治疗组总有效率为91.38%,对照组总有效率为74.14%,2 组比较,差异有统计学意义(P<0.05)。治疗后,2 组Peabody 精细运动发育量表(PDMS-FM) 中抓握能力、视觉-运动系统评分及精细运动功能评估量表(FMFM) 中视觉追踪、上肢关节活动能力、抓握能力、操作能力、手眼协调能力评分均较治疗前升高(P<0.05),治疗组上述各项精细运动细则评分均高于对照组(P<0.05)。治疗后,2 组肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6) 水平均较治疗前降低,IGF-1 水平均较治疗前升高(P<0.05);治疗组TNF-α、IL-6 水平均低于对照组,IGF-1 水平高于对照组(P<0.05)。治疗组和对照组不良反应发生率分别为1.72%和3.45%,2 组比较,差异无统计学意义(P>0.05)。结论:当归四逆汤加减熏洗联合益脑增智针法治疗小儿脑瘫临床疗效确切,可提高患儿的精细运动功能,降低炎症因子水平。

    Abstract:

    Abstract:Objective:To observe the clinical effect of fuming-washing therapy with modified Danggui Sini tang combined with Yinao Zengzhi needling method for child cerebral palsy. Methods: A total of 116 cases of children with cerebral palsy were selected and divided into the control group and the treatment group according to the random number table method,58 cases in each group. The control group was given Yinao Zengzhi needling method,and the treatment group was additionally given fuming- washing therapy with modified Danggui Sini tang based on the treatment of the control group. Both groups were continuously treated for 12 weeks,five times a week. The clinical effect as well as the levels of inflammatory factors and insulin-like growth factor-1(IGF-1) in serum was compared between the two groups. Fine motor of children before and after treatment was tested. The incidence of adverse reactions was recorded. Results:The total effective rate was 91.38% in the treatment group and 74.14% in the control group,the difference being significant(P<0.05). After treatment,the scores of hold- abilities and visual- motor system in Peabody Developmental Motor Scale- Fine Motor(PDMS- FM) as well as the scores of visual tracking,activity of upper limb motion,hold- abilities,performance ability,and hand- eye coordination in Fine Motor Function Measure Scale(FMFM) in the two groups were increased when compared with those before treatment (P<0.05);each scores above in the treatment group were higher than that in the control group(P<0.05).After treatment,the levels of tumor necrosis factor- α(TNF- α) and interleukin- 6(IL- 6) in the two groups were decreased when compared with those before treatment,and the levels of IGF- 1 were increased(P<0.05);the levels of TNF- α and IL- 6 in the treatment group were lower than those in the control group,and the level of IGF-1 was higher than that in the control group(P<0.05). The incidence of adverse reactions was 1.72% in the treatment group and 3.45% in the control group, there being no significance in the difference(P>0.05). Conclusion:The therapy of fuming-washing therapy with modified Danggui Sini tang combined with Yinao Zengzhi needling method has defined clinical effect in treating child cerebral palsy,which can improve fine motor function and reduce levels of inflammatory factors.

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许华,李彦枝,胡志娟.当归四逆汤加减熏洗联合益脑增智针法治疗小儿脑瘫临床研究[J].新中医,2020,52(20):24-27

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  • 在线发布日期: 2020-10-19
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