| 摘要: |
| 目的：观察加味星蒌承气汤治疗急性脑梗死痰热腑实证的临床疗效。方法：选取123 例急性脑梗死痰热腑实证患者，按随机数字表法分为观察组82 例与对照组41 例。2 组均给予抗凝、溶栓等治疗，对照组在此基础上给予乳果糖口服液治疗，观察组则给予加味星蒌承气汤治疗，2 组均治疗7 d。比较2 组治疗前后白细胞介素-6（IL-6） 水平、中医证候积分及美国国立卫生研究院卒中量表（NIHSS） 评分，治疗结束后比较2 组临床疗效。结果：治疗后，2 组IL-6 水平均较治疗前下降（P＜0.01），组间比较，差异无统计学意义（P＞0.05）。治疗后，2 组中医证候积分均较治疗前降低（P＜0.01），观察组中医证候积分低于对照组（P＜0.01）。治疗后，2 组NIHSS 评分均较治疗前降低（P＜0.01），观察组NIHSS 评分低于对照组（P＜0.01）。观察组总有效率（93.90%） 高于对照组（80.49%），差异有统计学意义（P＜0.05）。结论：加味星蒌承气汤治疗急性脑梗死痰热腑实证，可以有效缓解患者的临床症状，改善其神经功能，减轻炎症反应。 |
| 关键词: 急性脑梗死 痰热腑实证 星蒌承气汤 白细胞介素-6 中医证候 美国国立卫生研究院卒中量表 |
| DOI： |
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| 基金项目: |
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| Clinical Study on Modified Xinglou Chengqi Tang for Acute Cerebral Infarction withPhlegm-Heat Bowel Excess Syndrome |
| HE Xiao |
| (单篇PDF全文查阅请上中国知网下载阅读（中国知网电子版刊出时间：纸刊刊出日期一个月左右）) |
| Abstract: |
| Abstract： Objective： To observe the clinical effect of modified Xinglou Chengqi tang for acute cerebral infarction with
phlegm-heat bowel excess syndrome. Methods：A total of 123 cases of patients with acute cerebral infarction with phlegmheat
bowel excess syndrome were divided into the observation group and the control group according to the random number
table method， 82 and 41 cases in each group respectively. Both groups were given treatments such as antiplatelet
aggregation and thrombolysis，the control group was additionally treated with lactulose oral liquid，and the observation group
was treated with modified Xinglou Chengqi tang. Both groups were treated for seven days. The levels of interleukin- 6(IL-6)，
Chinese medicine syndrome scores and the scores of National Institutes of Health Stroke Scale(NIHSS) before and after
treatment were compared between the two groups. After treatment， the clinical effect was compared between the two
groups. Results：After treatment，the levels of IL- 6 in the two groups were decreased when compared with those before
treatment(P＜0.01)， but there was no significance in the difference among the two groups(P＞0.05). After treatment， the
Chinese medicine syndrome scores in the two groups were decreased when compared with those before treatment(P＜
0.01)， and the scores in the observation group were lower than those in the control group(P＜0.01). After treatment， the
scores of NIHSS in the two groups were decreased when compared with those before treatment(P＜0.01)；the score in the
observation group was lower than that in the control group(P＜0.01). The total effective rate was 93.90% in the observation
group， higher than that of 80.49% in the control group， the difference being significant(P＜0.05). Conclusion： Modified
Xinglou Chengqi tang for patients acute cerebral infarction with phlegm-heat bowel excess syndrome，can effectively relieve
the clinical effect of them，improve the neurological function and reduce inflammatory reactions. |
| Key words: Keywords： Acute cerebral infarction Phlegm- heat bowel excess syndrome Xinglou Chengqi tang Interleukin- 6 Chinese medicine syndrome National Institutes of Health Stroke Scale |
