芪羌牛蒡散联合西药治疗前列腺增生症临床研究
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R697+.32

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2019年医疗卫生事业发展专项资金(传承发展中医药事业) 资助;广东省中医药局中医药科研项目(20191374)


Clinical Study of Qiqiang Niubang Power Combined with Western Medicine for Prostatic Hyperplasia
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    摘要:

    目的:观察芪羌牛蒡散联合西药治疗前列腺增生症的临床疗效。方法:将前列腺增生症老年患者120 例随机分为试验组和对照组,每组60 例。2 组均根据患者病情选用非那雄胺、坦洛辛缓释胶囊治疗,试验组加用芪羌牛蒡散治疗,共治疗3 个月。观察比较2 组治疗前后国际前列腺症状评分(IPSS)、生活质量(QOL) 评分,以及治疗前后前列腺体积、膀胱残余尿量(PVR)、最大尿流率(Qmax) 变化。结果:治疗过程中试验组病例脱落4 例,对照组脱落5 例。治疗1 个月、3 个月,2 组患者IPSS、QOL 评分均较治疗前明显下降(P<0.05),且试验组两项评分均明显低于对照组(P<0.05)。治疗1 个月、3 个月,2 组患者PVR 值较治疗前明显下降(P<0.05),Qmax 值明显上升(P<0.05),且试验组两项指标改善均明显优于对照组(P<0.05)。治疗后1 个月,2 组前列腺体积与治疗前及组间比较,差异均无统计学意义(P>0.05);治疗3 个月,2 组前列腺体积均较治疗前明显缩小(P<0.05),但2 组间比较,差异无统计学意义(P>0.05)。所有完成试验的患者治疗前后均未出现血、尿常规及肝肾功能异常情况。结论:芪羌牛蒡散联合西药治疗前列腺增生症疗效显著。

    Abstract:

    Abstract: Objective: To observe the clinical effect of Qiqiang Niubang powder combined with western medicine for prostatic hyperplasia. Methods: A total of 120 cases of patients with prostatic hyperplasia were randomly divided into the experiment group and the control group, 60 cases in each group. Both groups were treated with finasteride tablets and tamsulosin hydrochloride sustained release capsules according to their disease condition, and the experiment group was additionally treated with Qiqiang Niubang powder. Both groups were treated for three months. Before and after treatment,in the two groups,the scores of International Prostate Symptom Score(IPSS) and Quality of Life(QOL),as well as the changes in prostate volume, postvoid residual volume(PVR) and maximum urinary flow rate(Qmax) were observed and compared. Results:During treatment,there were four cases lost in the experiment group and five cases in the control group. After onemonth and three- month treatment, the scores of IPSS and QOL in the two groups were significantly decreased when compared with those before treatment(P<0.05),and the two scores in the experiment group were significantly lower than those in the control group(P<0.05). After one-month and three-month treatment,the values of PVR in the two groups were significantly decreased and Qmax were significantly increased when compared with those before treatment(P<0.05), and the above two indexes in the experiment group were better than those in the control group(P<0.05). As for the prostate volume, after one month of treatment, there was no significant difference being found when compared with that before treatment, nor when comparing that between the two groups(P>0.05); after three months of treatment, the prostate volume in the two groups was significantly decreased when compared with that before treatment(P<0.05),but there was no significant difference being found in the comparison between the two groups(P>0.05). There was no abnormal condition of blood routine, urine routine, or the function of the liver and the kidney before and after treatment in all patients that had finished the experiment. Conclusion: The therapy of Qiqiang Niubang powder combined with western medicine has significant curative effect in treating prostatic hyperplasia.

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崔建锋,江洪亮,张健俊,何国卫,柯桂任,李健聪.芪羌牛蒡散联合西药治疗前列腺增生症临床研究[J].新中医,2020,52(14):85-87

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  • 在线发布日期: 2020-07-20
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