Abstract： Objective： To observe the clinical effect of “Sancai syndrome differentiation and treatment method” with yin-yang in equilbrium for insomnia induced by cervical spondylosis. Methods：A total of 60 cases of patients with insomnia induced by cervical spondylosis were selected and randomly divided into the experiment group and the control group. The experiment group was treated with “Sancai syndrome differentiation and treatment method”with yin- yang in equilbrium， and the control group was given the oral administration of estazolam before sleep. Both groups were treated for 14 days. The scores of Pittsburgh Sleep Quality Index(PSQI) before and after treatment and curative effect were compared between the two groups. Results： After treatment， the scores of PSQI in the two groups were improved when compared with those before treatment， and the improvement in the experiment group was better than that in the control group(P＜0.05). After treatment， the total effective rate was 93.33% in the experiment group and 80.00% in the control group， the difference being significant(P＜0.05). Conclusion：“Sancai syndrome differentiation and treatment method” with yin-yang in equilbrium has good curative effect in treating insomnia induced by cervical spondylosis.