中医特色抗癌疗法和护理对结肠癌术后患者胃肠功能和免疫功能的影响
DOI:
作者:
作者单位:

作者简介:

通讯作者:

中图分类号:

R735.3

基金项目:

河南省中医药科学研究专项课题(2017ZY2006)


Effect of Anticancer Therapy and Nursing with Characteristics of Chinese Medicine on Gastrointestinal Function and Immune Function of Postoperative Patients with Colon Cancer
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    目的:研究在结肠癌术后采用中医特色抗癌疗法和护理干预的临床疗效。方法:将80例结肠癌术后患者按随机数字表法分为观察组和对照组各40例。对照组采用常规疗法和护理,观察组在对照组基础上采用中医特色抗癌疗法和护理干预。观察2组治疗前后胃肠功能恢复情况、细胞免疫指标水平、体液免疫指标水平、血清肿瘤标志物水平,并评定临床疗效。结果:观察组总有效率为92.50%,高于对照组77.50%(P<0.05)。观察组术后肠鸣音恢复时间、首次排气时间和首次排便时间均明显短于对照组(P<0.05)。治疗后,2组外周血CD3+、CD4+ T淋巴细胞比例、CD4+/CD8+比值较治疗前升高(P<0.05),CD8+ T淋巴细胞比例较治疗前降低(P<0.05);且观察组外周血CD3+、CD4+ T淋巴细胞比例、CD4+/CD8+比值高于对照组(P<0.05),CD8+T淋巴细胞比例低于对照组(P<0.05)。治疗后,2组患者免疫球蛋白G(IgG)、免疫球蛋白A(IgA)、免疫球蛋白M(IgM) 各项指标较治疗前升高(P<0.05),且观察组的改善程度优于对照组(P<0.05)。治疗后,2组患者血清糖类抗原199(CAl99) 和癌胚抗原(CEA) 水平较治疗前明显降低(P<0.05),且观察组的降低程度大于对照组(P<0.05)。结论:在结肠癌术后采用中医特色抗癌疗法和护理干预,能够明显改善患者胃肠功能和免疫功能,降低血清CAl99和CEA,抑制肿瘤的发生发展。

    Abstract:

    Abstract: Objective: To study the clinical effect of anticancer therapy and nursing intervention with characteristics of Chinese medicine of postoperative patients with colon cancer. Methods: Divided 80 cases of postoperative patients with colon cancer into the observation group and the control group according to random number table,40 cases in each group. The control group received routine therapy and nursing,while the observation group additionally received anticancer therapy and nursing intervention with characteristics of Chinese medicine. Observed the recovery of gastrointestinal function,the indexes of cellular immunity,the indexes of humoral immunity and the levels of serum tumor markers in both groups before and after treatment,and evaluated the clinical effect. Results:The total effective rate was 92.50% in the observation group,higher than 77.50% in the control group(P<0.05). After operation,the recovery time of gurgling sound,the time of first exsufflation and the time of first defecation in the observation group were significantly shorter than those in the control group(P<0.05).After treatment,the proportions of CD3+ and CD4+ in peripheral blood and the ratio of CD4+/CD8+ in both groups were higher than those before treatment(P<0.05),and the proportions of CD8 + were lower than those before treatment(P<0.05);the proportion of CD3+ and CD4+ in peripheral blood and the ratio of CD4+/CD8+ in the observation group were higher than those in the control group(P<0.05),and the proportion of CD8 + was lower than that in the control group(P<0.05). After treatment,the indexes of immune globulin G(IgG), immune globulin A(IgA) and immune globulin M(IgM) in both groups were respectively higher than those before treatment(P<0.05), and each index above in the observation group was improved better than that in the control group(P<0.05). After treatment, the levels of carbohydrate antigen 199(CA199) and carcinoembryonic antigen(CEA) in both groups were significantly lower than those before treatment(P<0.05),and the levels of CA199 and CEA in the observation group were decreased more significantly than those in the control group(P<0.05).Conclusion:The application of anticancer therapy and nursing intervention with characteristics of Chinese medicine has good effect in treating postoperative patients with colon cancer, which can significantly improve gastrointestinal function and immune function,decrease the levels of serum CA199 and CEA,and inhibit the initiation and progression of tumor.

    参考文献
    相似文献
    引证文献
引用本文

徐秀敏,刘双凤,刘正阁.中医特色抗癌疗法和护理对结肠癌术后患者胃肠功能和免疫功能的影响[J].新中医,2020,52(11):151-154

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2020-06-04
  • 出版日期: