知柏地黄汤加味对青春期大骨龄偏矮女童骨龄指数的影响
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R681.1

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河南省中医药科学研究专项(2018ZY2066)


Effect of Modified Zhibai Dihuang Tang on Bone Age Index in Adolescent Girls with High Bone Age and Short Stature
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    摘要:

    目的:观察知柏地黄汤加味对青春期大骨龄偏矮女童骨龄指数的影响。方法:观察47 例青春期大骨龄偏矮女童,中医辨证为阴虚火旺型,或兼脾虚痰湿或兼肝郁,辨证予以知柏地黄汤加味治疗,疗程为6 个月,比较干预前后身高、体质量、体质量指数、骨龄指数以及骨龄预测成年终身高的变化。结果:青春期大骨龄偏矮女童予以知柏地黄汤加味干预后,身高较干预前增长,体质量指数较干预前下降,差异均有统计学意义(P<0.05)。骨龄及骨龄指数也比干预前下降,差异有统计学意义(P<0.05),预测身高由干预前低于遗传身高改变为与遗传身高比较,差异无统计学意义(P>0.05)。结论:对青春期大骨龄偏矮女童,采取知柏地黄汤加味辨证干预可以抑制骨龄生长速度、提高身高生长空间,从而利于终身高的改善。

    Abstract:

    Abstract:Objective:To observe the effect of modified Zhibai Dihuang tang on bone age index in adolescent girls with high bone age and short stature. Methods:A total of 47 cases of adolescent girls with high bone age and short stature,who were of yin deficiency with effulgent fire type, complicated with liver depression or spleen deficiency and phlegmdampness, were observed according to Chinese medicine syndrome differentiation. Based on syndrome differentiation,they were treated with modified Zhibai Dihuang tang for six months. Before and after intervention,the changes in height,body mass,body mass index,bone age index and adult final height predicted by bone age were compared. Results:After the intervention of modified Zhibai Dihuang tang for adolescent girls with high bone age and short stature, the height was lengthened when compared with that before intervention, and the body mass index was decreased, the difference being significant(P<0.05). Bone age and bone age index were also decreased when compared with that before intervention,the difference being significant(P<0.05). Before intervention, the predicted height was lower than genetic height; after intervention, there was no significant difference being found in the comparison between the predicted height and genetic height(P>0.05). Conclusion: The application of modified Zhibai Dihuang tang for adolescent girls with high bone age and short stature can inhibit bone age growth rate and increase the growth space of height, which is conducive to the improvement of final height.

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张永艳,琚玮,蒋会莉.知柏地黄汤加味对青春期大骨龄偏矮女童骨龄指数的影响[J].新中医,2020,52(19):47-49

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  • 在线发布日期: 2020-10-12
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