| 摘要: |
| 目的：观察加味柴胡疏肝散联合多潘立酮治疗肝郁气滞证功能性消化不良的临床疗效。方法：将80例肝郁气滞证功能性消化不良患者随机分为西药组和联合组各40例，西药组给予黛力新、多潘立酮治疗，联合组给予加味柴胡疏肝散联合多潘立酮治疗，观察比较2 组中医证候积分、临床疗效、负面情绪状况及随访6 个月的复发情况。结果：总有效率联合组为95.0%，西药组为80.0%，2组比较，差异有统计学意义（P＜0.05）。治疗后，2组中医证候积分均较治疗前明显降低（P＜0.05）；且联合组积分明显低于西药组（P＜0.05）。治疗后，2组患者HAMA、HAMD评分均较治疗前明显降低（P＜0.05），且联合组两项评分均明显低于西药组（P＜0.05）。复发率联合组为2.6%，西药组为25.0%，2组比较，差异有统计学意义（P＜0.05）。不良反应发生率联合组为7.5%，西药组为5.0%，2组比较，差异无统计学意义（P＞0.05）。结论：加味柴胡疏肝散联合黛力新、多潘立酮治疗肝郁气滞证功能性消化不良疗效显著，可有效减轻患者症状，改善患者负面情绪，且复发率低，预后良好。 |
| 关键词: 功能性消化不良 肝郁气滞 中西医结合疗法 加味柴胡疏肝散 多潘立酮 |
| DOI： |
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| 基金项目: |
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| Clinical Study on Modified Chaihu Shugan Powder Combined with Domperidone forFunctional Dyspepsia with Liver Constraint and Qi Stagnation Syndrome |
| XU Li,ZHU Yan |
| () |
| Abstract: |
| Abstract： Objective： To observe the clinical effect of modifiedChaihuShugan powder combined with domperidone for
functional dyspepsia with liver constraint and qi stagnation syndrome. Methods：A total of 80 cases of patients with functional
dyspepsia with liver constraint and qi stagnation syndrome were randomly divided into the western medicine group and the
combination group，40 cases in each group.The western medicine group was treated with deanxit and domperidone，and the
combination group was given modifiedChaihuShugan powder combined with domperidone.The Chinese medicine syndrome
scores，clinical effect and negative emotions as well as the recurrence during the six- month follow- up in the two groups
were observed and compared. Results： The total effective rate was 95.0% in the combination group and 80.0% in the
western medicine group，the difference being significant(P＜0.05). After treatment，the Chinese medicine syndrome scores
in the two groups were significantly decreased when compared with those before treatment(P＜0.05)； the score in the
combination group was significantly lower than that in the western medicine group(P＜0.05). After treatment，the scores of
HAMA and HAMD in the two groups were significantly decreased when compared with those before treatment(P＜0.05)，and
the above two scores in the combination group were significantly lower than those in the western medicine group(P＜0.05).
The recurrence rate was 2.6% in the combination group and 25.0% in the western medicine group， the difference being
significant(P＜0.05). The incidence of adverse reactions was 7.5% in the combination group and 5.0% in the western medicine
group， there being no significance in the difference(P＞0.05). Conclusion： The therapy of modifiedChaihuShugan powder
combined with deanxit and domperidone has significant curative effect in treating functional dyspepsia with liver constraint and
qi stagnation syndrome，which can effectively alleviate thesymptoms，improve their negative emotions with low recurrence
rate and good prognosis. |
| Key words: Keywords： Functional dyspepsia Liver constraint and qi stagnation Integrated Chinese and western medicine
therapy Modified ChaihuShugan powder Domperidone |
