去腐生新膏联合环丙沙星治疗肛周脓肿术后临床研究
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Clinical Study on Qufu Shengxin Ointment Combined with Ciprofloxacin for Patients After Operation for Perianal Abscess
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    摘要:

    目的:观察去腐生新膏换药联合抗生素治疗肛周脓肿术后的临床疗效。方法:将肛周脓肿术后患者 60 例随机分为观察组和对照组,各 30 例。对照组术后常规换药并给予环丙沙星口服治疗,观察组给予去腐生新膏外涂联合环丙沙星口服治疗。观察比较 2 组创面疼痛、创面渗液、肉芽生长情况及创面愈合时间,并统计 2 组临床疗效。结果:治愈率观察组为 90.00%,对照组为 43.33%,2 组比较,差异有统计学意义(P<0.05)。术后 7 d、14 d、28 d,2 组疼痛视觉模拟评分法(VAS)评分均较治疗前明显下降(P<0.05),且在术后 28 d 时,观察组 VAS 评分明显低于对照组(P<0.05)。术后 7 d、14 d、28 d,2 组患者创面渗液评分均较治疗前明显下降(P<0.05),且观察组各个时间点的评分均低于对照组(P<0.05)。术后 7 d、14 d、28 d,观察组患者肉芽生长评分均低于对照组,差异有统计学意义(P<0.05)。创面平均愈合时间观察组短于对照组,差异有统计学意义(P< 0.05)。结论:肛周脓肿术后应用去腐生新膏联合环丙沙星治疗,可减轻患者疼痛,加速创面愈合,临床疗效显著。

    Abstract:

    Abstract: Objective: To observe the clinical effect of Qufu Shengxin ointment and dressing change combined with antibiotics for patients after operation for perianal abscess. Methods:A total of 60 cases of patients after operation for perianal abscess were randomly divided into the observation group and the control group,30 cases in each group. After operation, the control group was given oral administration of ciprofloxacin after routine dressing change,and the observation group was given external application of Qufu Shengxin ointment combined with oral administration of ciprofloxacin. The wound pain, wound exudate,growth of granulation and wound healing time in the two groups were observed and compared;the clinical effect in the two groups was calculated. Results:The cure rate was 90.00% in the observation group and 43.33% in the control group,the difference being significant(P<0.05). On the 7th,14th and 28th day after operation respectively,VAS scores in the two groups were significantly decreased when compared with those before treatment(P<0.05);on the 28th day after treatment,VAS score in the observation group was significantly lower than that in the control group(P<0.05). On the 7th,14th and 28th day after operation respectively,the scores of wound exudate in the two groups were significantly decreased when compared with those before treatment(P<0.05),and the scores at each time point in the observation group were lower than those in the control group(P<0.05). On the 7th, 14th and 28th day after operation respectively, the scores of granulation growth in the observation group were lower than those in the control group,the difference being significant(P<0.05). The average wound healing time in the observation group was shorter than that in the control group, the difference being significant(P<0.05). Conclusion:The application of Qufu Shengxin ointment combined with ciprofloxacin for patients after operation for perianal abscess can reduce the pain and accelerate wound healing,with significant clinical effect.

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杨泽辉.去腐生新膏联合环丙沙星治疗肛周脓肿术后临床研究[J].新中医,2020,52(22):80-82

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  • 在线发布日期: 2020-11-27
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