| 摘要: |
| 目的：观察柴胡桂枝干姜汤加减联合雷火灸治疗腹泻型肠易激综合征 （IBS-D） 少阳太阴寒热利证的临床效果。方 法：选取 IBS-D 少阳太阴寒热利证患者 60 例，随机分为治疗组和对照组各 30 例。治疗组给予柴胡桂枝干姜汤加减联合雷火灸治疗，对照组给予马来酸曲美布汀片联合双歧杆菌三联活菌胶囊治疗。比较 2 组大便性状、腹痛腹胀程度、排便频率评分，统计2 组胃肠道总体症状疗效，随访 2 个月，统计 2 组复发率。结果：治疗后，2 组大便性状、腹痛腹胀程度、排便频率评分均降低（P＜0.05）；治疗组大便性状、腹痛腹胀程度、排便频率评分均低于对照组（P＜0.05）。治疗组总有效率为 96.7%（29/30），对照组为 73.3% （22/30），治疗组总有效率高于对照组 （P＜0.05）。治疗组复发率为 0 （0/29），显著低于对照组的 13.64% （3/22），组间比较，差异有统计学意义（P＜0.05）。结论：柴胡桂枝干姜汤加减联合雷火灸治疗 IBS-D 少阳太阴寒热利证的临床效果较马来酸曲美布汀片联合双歧杆菌三联活菌胶囊更好，在改善患者症状及降低复发率方面有较大优势。 |
| 关键词: 腹泻型肠易激综合征 少阳太阴寒热利证 柴胡桂枝干姜汤加减 雷火灸 马来酸曲美布汀片 双歧杆菌三联活
菌胶囊 |
| DOI： |
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| 基金项目:福建中医药大学2018年临床专项校管课题立项（XB2018092） |
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| Clinical Study on Modified Chaihu Guizhi Ganjiang Tang Combined with Thunder-FireMoxibustion for Irritable Bowel Syndrome with Diarrhea with Shaoyang Taiyin ofCold，Heat and Diarrhea Syndrome |
| LUO Xiuqing,ZHANG Haojun,FAN Wendong,LYU Jinhuan |
| () |
| Abstract: |
| Abstract：Objective：To observe the clinical effect of modified Chaihu Guizhi Ganjiang tang combined with thunder-fire
moxibustion on patients with irritable bowel syndrome with diarrhea(IBS-D) with Shaoyang Taiyin of cold，heat and diarrhea
syndrome. Methods： A total of 60 patients with IBS- D with Shaoyang Taiyin of cold， heat and diarrhea syndrome were
selected and randomly divided into the treatment group and the control group，30 cases in each group. The treatment group
was treated with modified Chaihu Guizhi Ganjiang tang combined with thunder-fire moxibustion，and the control group was
treated with trimebutin maleate tablets combined with bifidobacterium triple viable capsules. The scores of stool
characteristics， degree of abdominal pain and distension， and defecation frequency were compared between the two
groups. The overall gastrointestinal symptoms and effect in the two groups were counted. The recurrence rate in the two
groups was counted after follow-up for two months. Results：After treatment，the scores of stool characteristics，degree
of abdominal pain and distension， and defecation frequency were decreased(P＜0.05)； the above three scores in the
treatment group were lower than those in the control group(P＜0.05). The total effective rate was 96.7% (29/30) in the
treatment group and 73.3%(22/30) in the control group；the total effective rate in the treatment group was higher than that in
the control group(P＜0.05). The recurrence rate in the treatment group was 0(0/29)，significantly lower than that of 13.64%(3/22) in the control group，the difference being significant(P＜0.05). Conclusion：The therapy of modified Chaihu Guizhi Ganjiang
tang combined with thunder- fire moxibustion has better clinical effect than the treatment of trimebutin maleate tablets
combined with bifidobacterium triple viable capsules in treating IBS- D patients with Shaoyang Taiyin of cold， heat and
diarrhea syndrome，which has great advantages in improving patients' symptoms and reducing recurrence rate. |
| Key words: Keywords：Irritable bowel syndrome with diarrhea Shaoyang Taiyin of cold,heat and diarrhea syndrome Modified
Chaihu Guizhi Ganjiang tang Thunder-fire moxibustion Trimebutin maleate tablets Bifidobacterium triple viable capsules |
