电针联合氢吗啡酮治疗瘀血停滞型中重度癌性疼痛临床研究
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R730.6; R246.5

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Clinical Study on Electroacupuncture Combined with Hydromorphone for Moderate and Severe Cancer Pain of Stagnation of Static Blood Type
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    摘要:

    目的:分析电针联合氢吗啡酮对瘀血停滞型中重度癌性疼痛患者的止痛效果,以及对患者生活质量的影响。方法:选取恶性肿瘤癌性疼痛患者80例,按照随机数字表法分为观察组和对照组各40例。对照组采用氢吗啡酮治疗,观察组采用氢吗啡酮联合电针治疗。记录2组治疗前后爆发痛发作次数、NRS评分、KPS评分、不良反应,以及氢吗啡酮平均每天使用量。结果:观察组止痛疗效总有效率为90.0%,显著高于对照组70.0%,差异有统计学意义(P<0.05)。治疗前,2组爆发痛发作次数、NRS评分、KPS评分比较,差异均无统计学意义(P>0.05)。治疗后,2组爆发痛发作次数、NRS评分降低,KPS评分升高;且观察组爆发痛发作次数、NRS评分低于对照组,KPS评分高于对照组;差异均有统计学意义(P<0.05)。观察组不良反应率为15.0%,显著低于对照组35.0%(P<0.05)。观察组氢吗啡酮平均每天使用量低于对照组(P<0.05)。结论:对瘀血停滞型中重度癌性疼痛患者采用电针联合氢吗啡酮治疗,止痛效果明显,不良反应少,有利于提高患者生活质量,值得临床推广。

    Abstract:

    To analyze the antalgic effect of electroacupuncture combined with hydromorphone on patients with moderate and severe cancer pain of stagnation of static blood type, and the effect on quality of life.Methods:A total of 80 cases of patients with cancer pain of malignant tumors were divided into the observation group and the control group according to the random number table method,40 cases in each group.The control group was treated with hydromorphone,and the observation group was additionally treated with electroacupuncture based on the treatment of the control group.The attack times of breakthrough pain,the scores of NRS and KPS,the adverse reactions before and after treatment and the average daily usage of hydromorphone in the two groups were recorded.Results:The total effective rate of antalgic effect was 90.0% in the observation group,significantly higher than that of 70.0% in the control group,the difference being significant(P < 0.05).Before treatment,compared the attack times of breakthrough pain and the scores of NRS and KPS in the two groups,there was no significance in the difference(P > 0.05).After treatment,the attack times of breakthrough pain and the scores of NRS in the two groups were decreased,while the scores of KPS were increased;the attack time of breakthrough pain and the score of NRS in the observation group were lower than those in the control group,while the score of KPS was higher;differences being significant(P < 0.05).The incidence of adverse reactions was 15.0%in the observation group,significantly lower than that of 35.0%in the control group(P<0.05).The average daily usage of hydromorphone in the observation group was less than that in the control group(P<0.05).Conclusion:The therapy of electroacupuncture combined with hydromorphone for patients with moderate and severe cancer pain of stagnation of static blood type has significant antalgic effect and few adverse reactions,which is conducive to improving quality of life of patients and worthy of clinical promotion.

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王灿.电针联合氢吗啡酮治疗瘀血停滞型中重度癌性疼痛临床研究[J].新中医,2019,51(10):242-244

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  • 在线发布日期: 2019-10-11
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