益气凉血祛瘀汤联合西药治疗晚期产后出血临床研究
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R714.46

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Clinical Study on Yiqi Liangxue Quyu Tang Combined with Western Medicine in the Treatment of Advanced Postpartum Hemorrhage
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    摘要:

    目的:观察益气凉血祛瘀汤联合西药治疗晚期产后出血的效果以及对炎症因子的影响。方法:选取120例晚期产后出血患者,按随机数字表法分为对照组和观察组各60例。对照组给予益母草片和头孢拉定胶囊治疗,观察组在对照组基础上联合益气凉血祛瘀汤治疗。比较2组中医证候评分、血清白细胞介素-6(IL-6)、C-反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α) 水平、出血停止时间、子宫复旧情况和临床疗效。结果:观察组总有效率为95.00%,显著高于对照组80.00%(P<0.05)。治疗前,2组血清炎症因子水平比较,差异无统计学意义(P>0.05)。治疗后,2组IL-6、CRP、TNF-α水平较治疗前明显降低,其中观察组IL-6、CRP、TNF-α水平低于对照组,差异均有统计学意义(P<0.05)。治疗前,2组中医证候评分比较,差异无统计学意义(P>0.05)。治疗后,2组中医证候评分均较治疗前降低,且观察组低于对照组,差异均有统计学意义(P<0.05)。治疗后,观察组出血停止时间和子宫三径均低于对照组(P<0.05)。结论:益气凉血祛瘀汤联合西药治疗晚期产后出血,通过降低炎症因子水平来改善患者病情,效果显著,值得推广。

    Abstract:

    To observe the effect of Yiqi Liangxue Quyu Tang combined with western medicine in the treatment of advanced postpartum hemorrhage in parturient women,and its effect on inflammatory factors.Methods:A total of 120 women with advanced postpartum hemorrhage were selected and divided into the control group and the observation group according to random number table method,60 cases in each group.The control group was treated with leonurus tablets and cefradin capsules,and the observation group was additionally treated with Yiqi Liangxue Quyu Tang based on the treatment of the control group.Chinese medicine syndrome scores,serum interleukin-6(IL-6),C-reactive protein(CRP),levels of tumor necrosis factor-α (TNF-α),bleeding cessation time,uterine regression and therapeutic effect were compared between the two groups.Results:The total effective rate was 95.00%in the observation group,significantly higher than that of 80.00%in the control group(P < 0.05).Before treatment,there was no statistically significant difference in the comparison of the levels of serum inflammatory cytokines between the two groups(P> 0.05).After treatment,the levels of IL-6,CRP and TNF-α in the two groups were significantly decreased when compared with those before treatment,and the above levels in the observation group were lower than those in the control group,differences being statistically significant(P<0.05).Before treatment,there was no statistically significant difference in the comparison of Chinese medicine syndrome scores between the two groups(P > 0.05).After treatment,Chinese medicine syndrome scores in both groups were decreased when compared with those before treatment,and those in the observation group were lower than those in the control group,differences being significant(P < 0.05).After treatment,the bleeding cessation time and three diameters of uterine in the observation group were all lower than those in the control group(P<0.05).Conclusion:The therapy of Yiqi Liangxue Quyu Tang combined with western medicine can improve the condition of patients with late postpartum hemorrhage by reducing the level of inflammatory factors,which is worthy of promotion and with significant therapeutic effect.

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张喜芝,范旭虹.益气凉血祛瘀汤联合西药治疗晚期产后出血临床研究[J].新中医,2019,51(10):187-189

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  • 在线发布日期: 2019-10-11
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