仙灵骨葆胶囊联合钙尔奇 D600 治疗骨质疏松症临床研究
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Clinical Study of Xianling Gubao Capsules Combined with Caltrate D600 for Osteoporosis
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    摘要:

    目的:观察仙灵骨葆胶囊联合钙尔奇D600治疗骨质疏松症的临床效果。方法:将骨质疏松症患者78例依据随机数字表法分为对照组和观察组各39例,对照组给予口服钙尔奇D600,观察组在对照组基础上服用仙灵骨葆胶囊,比较2组患者治疗前后的腰椎L2~4与股骨颈的骨密度、血钙、血磷。对2组患者在治疗过程中的不良反应情况进行比较。结果:治疗后,2组腰椎L2~4与股骨颈的骨密度均增高,与治疗前比较,差异有统计学意义(P<0.05)。在治疗后的组间比较中,观察组腰椎L2~4与股骨颈的骨密度均高于对照组,差异有统计学意义(P<0.05)。治疗后,2组血钙、血磷均增高,与治疗前比较,差异有统计学意义(P<0.05)。治疗后,组间比较,观察组血钙、血磷均高于对照组,差异有统计学意义(P<0.05)。治疗后,2组不良反应情况比较,差异无统计学意义(P>0.05)。结论:仙灵骨葆胶囊联合钙尔奇D600治疗骨质疏松症患者,可以改善骨密度,提升血钙与血磷浓度,安全性良好。

    Abstract:

    To observe the clinical effect of Xianling Gubao capsules combined with caltrate D600 for osteoporosis.Methods:According to the random number table, divided 78 cases of patients with osteoporosis into the control group and the observation group,with 39 cases in each group.Both groups received the oral administration of caltrate D600,while the observation group additionally took Xianling Gubao capsules.Compared the bone mineral density,blood calcium and serum phosphorus of lumbar vertebrae L2~4and femoral neck in the two groups before and after treatment.Compared the adverse reactions during the treatment between the two groups.Results: After treatment, bone mineral density of lumbar vertebrae L2~4and femoral neck increased in both groups,compared with that before treatment,difference being significant(P < 0.05).In the comparison between groups after treatment,the bone mineral density of both lumbar vertebrae L2~4and femoral neck in the observation group was higher than that in the control group,difference being significant(P < 0.05).After treatment,blood calcium and serum phosphorus were increased in both groups,compared with that before treatment,difference being significant(P < 0.05).After treatment,both blood calcium and serum phosphorus in the observation group were higher than those in the control group,difference being significant(P < 0.05).After treatment,there was no significant difference being found in the comparison of the adverse reactions in the two groups(P> 0.05).Conclusion:The application of Xianling Gubao capsules combined with caltrate D600 for patients with osteoporosis can improve the bone mineral density and increase the concentration of blood calcium and serum phosphorus with fairly good safety.

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党兴.仙灵骨葆胶囊联合钙尔奇 D600 治疗骨质疏松症临床研究[J].新中医,2019,51(10):162-164

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  • 在线发布日期: 2019-10-11
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