芪参益气滴丸结合西药治疗气虚血瘀型高龄老年心肌梗死临床研究
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R542.2+2

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杭州市卫生计生科技计划项目 (2015B60)


Clinical Study on Qishen Yiqi Dropping Pills Combined with Western Medicine in the Treatment of Myocardial Infarction with Qi Deficiency and Blood Stasis Type in Senile Patients
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    摘要:

    目的:观察芪参益气滴丸结合西药治疗气虚血瘀型高龄老年心肌梗死的临床疗效。方法:将80例高龄心肌梗死患者(气虚血瘀证)按接诊先后顺序随机分为中西医组和对照组,每组各40例。对照组采用常规西药治疗,中西医组在对照组的基础上加用芪参益气滴丸治疗;治疗6周后观察并比较2组临床疗效、心室重构指标 [左室舒张末期容积(LVEDV)、左室收缩末期容积(LVESV)、左室舒张末期内径(LVDd)、收缩末期内径(LVDs)]以及心功能指标 [每搏量(SV)、有效心输出量(CO)、心脏指数(CI)、左室射血分数(LVEF)]。结果:总有效率中西医组为90.00%,对照组为75.00%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组心室重构各项指标LVEDV、LVESV、LVDd、LVDs值均较治疗前明显降低(P<0.05),且中西医组上述各项指标改善优于对照组(P<0.05)。治疗后,2组心功能指标SV、CO、CI、LVEF值均较治疗前明显升高(P<0.05),且中西医组上述各项指标改善优于对照组(P<0.05)。结论:芪参益气滴丸联合西药治疗气虚血瘀证心肌梗死高龄老年人患者疗效显著,可有效改善患者心功能,帮助其恢复心室重构。

    Abstract:

    To observe the clinical effect of the therapy of Qishen Yiqi Dropping Pills combined with western medicine in the treatment of myocardial infarction with qi deficiency and blood stasis type in elderly patients.Methods:A total of 80 elderly patients with myocardial infarction(qi deficiency and blood stasis syndrome)were randomly divided into the Chinese and western medicine group and the control group,40 cases in each group.The control group was treated with conventional western medicine,and the Chinese and western medicine group was additionally treated with Qishen Yiqi Dropping Pills based on the treatment of the control group.Six weeks after treatment,the clinical effect and the changes in the ventricular remodeling indexes including left ventricular end-diastolic volume(LVEDV),left ventricular end-systolic volume(LVESV), left ventricular end-diastolic diameter(LVDd)and left ventricular end-systolic diameter(LVDs), and the cardiac function indexes including stroke volume(SV), effective cardiac output(CO), cardiac index(CI), left ventricular ejection fraction(LVEF)in the two groups were observed and compared.Results:The total effective rate was 90.00%in the Chinese and western medicine group and 75.00%in the control group,the differences being significant(P<0.05).After treatment,the levels of each ventricular remodeling index including LVEDV,LVESV,LVDd and LVDs in the two groups were significantly decreased when compared with those before treatment(P < 0.05),and the improvement of the above indexes in Chinese and western medicine group was better than that in control group(P< 0.05).After treatment,the levels of SV,CO,CI and LVEF in the two groups were significantly increased when compared with those before treatment(P < 0.05),and the improvement of the above indexes in the Chinese and western medicine group was better than that in the control group(P<0.05).Conclusion:The therapy of Qishen Yiqi Dropping Pills combined with western medicine is effective in treating elderly patients of myocardial infarction with qi deficiency and blood stasis syndrome,which can effectively improve their cardiac function and help recover the ventricular remodeling.

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郦虹,吴玉泉,陈晓娜,宋添晶,孟冉.芪参益气滴丸结合西药治疗气虚血瘀型高龄老年心肌梗死临床研究[J].新中医,2019,51(10):81-84

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  • 在线发布日期: 2019-10-11
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