化痰脉通片联合西药治疗H型高血压痰瘀互结证临床研究
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R544.1

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新疆维吾尔自治区自然科学基金项目 (2015211C144)


Clinical Observation of Huatan Maitong Tablets Combined with Western Medicine for H-type Hypertension with Syndrome of Intermingled Phlegm and Blood Stasis
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    摘要:

    目的:观察化痰脉通片联合西药治疗H型高血压痰瘀互结证的临床疗效。方法:选取80例痰瘀互结型H型高血压患者,按血同型半胱氨酸(Hcy) <25 μmol/L、Hcy≥25 μmol/L分为2组,每组40例,组内再分为试验组和对照组各20例。两试验组均予化痰脉通片加苯磺酸氨氯地平和叶酸治疗,两对照组予苯磺酸氨氯地平加叶酸治疗。观察4组治疗前后Hcy水平及中医证候积分的变化。结果:治疗后,4组Hcy水平均较治疗前降低(P<0.05)。治疗后,2组(Hcy<25 μmol/L)头重如裹、手足麻木及试验组胸脘痞闷、纳呆恶心、身重困倦、胸痛心悸积分均较治疗前降低(P<0.05),试验组头重如裹、胸脘痞闷、纳呆恶心、身重困倦、手足麻木积分均低于对照组(P<0.05)。治疗后,2组(Hcy≥25 μmol/L)头重如裹、纳呆恶心、身重困倦及试验组胸痛心悸、手足麻木积分均较治疗前降低(P<0.05),试验组头重如裹、纳呆恶心、身重困倦及手足麻木积分均低于对照组(P<0.05)。结论:化痰脉通片联合西药治疗痰瘀互结型H型高血压,对降低Hcy水平及改善中医证候均有确切疗效,尤其对头重如裹、纳呆恶心、身重困倦及手足麻木改善效果明显。

    Abstract:

    Objective:To observe the clinical effect of Huatan Maitong tablets combined with western medicine for H-type hypertension with syndrome of intermingled phlegm and blood stasis.Methods:Selected 80 cases of patients with H-type hypertension of intermingled phlegm and blood stasistype and divided them into two groupsaccording to Homocysteine(Hcy)<25 μmol/L and Hcy≥25 μmol/L,40 cases in each group.The two groups were further divided into the experiment groups and the control groups respectively,20 cases in each group.The two experiment groups were treated with Huatan Maitong tablets combined with amlodipine besylate and folic acid,while the two control groups were treated combined with amlodipine besylate and folic acid.Observed the changes of Hcy levels and Chinese medicine syndrome scores in the four groups before and after treatment.Results:The Hcy levels of the four groups were decreased when compared with those before treatment(P<0.05).After treatment,the scores of head heaviness,numbness of hands and feet in the two groups(Hcy<25 μmol/L)and the scores of abdominal fullness and chest distress,anorexia and nausea,sleepiness and chest pain and palpitation in the experiment group were all decreased when compared with those before treatment(P<0.05);the scores of head heaviness,abdominal fullness and chest distress,anorexia and nausea,sleepiness and numbness of hands and feet in the experiment group were lower than those in the control group(P<0.05).After treatment,the scores of head heaviness,anorexia and nausea,sleepiness in the two groups(Hcy≥25 μmol/L)and the scores of chest pain and palpitation and numbness of hands and feet in the experiment group were all decreased when compared with those before treatment(P<0.05);the scores of head heaviness,anorexia and nausea,sleepiness and numbness of hands and feet in the experiment group were lower than those in the control group(P<0.05).Conclusion:The application of Huatan Maitong tablets combined with western medicine for H-type hypertension of intermingled phlegm and blood stasis type has a definite curative effect in reducing the Hcy levels in patients and improving Chinese medicine syndrome scores.Especially for head heaviness,anorexia and nausea,sleepiness and numbness of hands and feet,the effect is obvious.

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何佳,朱忠帅,张莉晶.化痰脉通片联合西药治疗H型高血压痰瘀互结证临床研究[J].新中医,2018,50(12):60-63

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  • 在线发布日期: 2018-12-09
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