特发性肺纤维化中医证候规律研究
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R541.6

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国家自然科学基金项目 (81574100);国家中医临床研究基地业务建设第二批科研专项项目 (NJDZX2015154)


Regularity Study on Chinese Medicine Syndrome of Idiopathic Pulmonary Fibrosis
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    摘要:

    目的:分析特发性肺纤维化(Idiopathic pulmonary fibrosis,IPF)中医证候分布特点,揭示IPF中医证候的分布规律,为建立IPF中医证候诊断标准提供依据。方法:检索CBM、CNKI、TCM、VIP数据库中有关IPF中医证候的全部文献并进行筛选,用SPSS 20.0对数据进行统计描述、因子分析及聚类分析。结果:收集的401篇文献中≥8%的常见症状有60个,因子分析、聚类分析及频数统计的常见证候有5种,并得出常见证候的主次症分布特征。结论:以文献研究为基础的IPF的中医常见证候有5种:痰瘀阻肺证、肺肾气虚证、肺气阴两虚证、痰热壅肺证、痰浊阻肺证;证候及其主次症分布具有一定的规律性,但仍需结合临床调查研究及专家经验为证候诊断标准的建立提供依据。

    Abstract:

    Objective:To analyze the distribution characteristics of Chinese medicine syndrome of idiopathic pulmonary fibrosis(IPF),reveal the distribution regularity of Chinese medicine syndrome of IPF,and provide reference for establishing the diagnostic criteria of Chinese medicine syndrome of IPF.Methods:Retrieved and screened all the literature about Chinese medicine syndrome of IPF on CBM,CNKI,TCM and VIP,and conducted statistical description,factor analysis and cluster analysis via SPSS 20.0.Results:60 common symptoms were found≥ 8%in 401 pieces of literature collected,5 types of common syndrome were found by means of factor analysis,cluster analysis and frequency statistics,and the distribution characteristics of major and minor symptoms of common syndrome were thereby concluded.Conclusion:5 types of common Chinese medicine syndrome of IPF have been found on the basis of literature research:syndrome of phlegm blocking the lung,lung-kidney qi deficiency syndrome,lung qi-yin deficiency syndrome,syndrome of phlegm-heat stagnating the lung and syndrome of phlegm-turbidity blocking the lung.The distribution of syndrome and its major and minor symptoms shows regularity to some extent,but it still needs to be combined with the clinical research and expert experience so as to provide reference for the establishment of diagnostic criteria of Chinese medicine syndrome.

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张南星,王至婉.特发性肺纤维化中医证候规律研究[J].新中医,2018,50(12):31-35

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  • 在线发布日期: 2018-12-09
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