康复新液干预鼻咽癌放射性治疗后口腔黏膜反应临床观察
DOI:
作者:
作者单位:

作者简介:

通讯作者:

中图分类号:

R739.6

基金项目:

杭州市科技计划项目(20130733Q45)


Clinical Observation of Kangfuxin Liquid in the Intervention for Oral Mucosa Reaction after Radiotherapy of Nasopharyngeal Carcinoma
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    目的:观察康复新液干预鼻咽癌放射性治疗后口腔黏膜反应的临床效果。方法:将4 6例鼻咽癌放射性治疗后出现口腔黏膜反应的患者按照随机数字表法分为对照组和观察组各23例。在放射性治疗期间,每天三餐后对照组应用生理盐水进行含漱,观察组应用康复新液进行含漱,均治疗2周。观察比较2组患者放射性治疗前后的口腔黏膜反应分级情况及疼痛程度[数字评分法(NR S)]与口腔黏膜反应持续时间。结果:治疗后,2组口腔黏膜反应程度均较治疗前改善(P<0.05),观察组口腔黏膜反应程度低于对照组(P<0.05)。观察组治疗1周口腔黏膜反应即消失的患者所占比例高于对照组,差异有统计学意义(P<0.01)。治疗后,2组NR S评分均较治疗前降低(P<0.05);观察组NR S评分低于对照组(P<0.05)。结论:以康复新液漱口能够有效减轻鼻咽癌放射性治疗后口腔黏膜反应的临床症状,减缓患者的口腔疼痛,缩短病程。

    Abstract:

    Objective:To observe the clinical effect of Kangfuxin liquid in the intervention for oral mucosa reaction after radiotherapy of nasopharyngeal carcinoma.M e th o d s:Divided 46 cases of patients with nasopharyngeal carcinoma who had oral mucosa reaction after radiotherapy into the control group and the observation group according to the random number table randomly,23 cases in each group.During the radiotherapy,the control group was rinsed with saline after three meals everyday,while the observation group was rinsed with Kangfuxin liquid.Observed the treatment for two weeks.Observed and compared the classification of oral muofcosa reaction in radiotherapy,the duration of oral mucosa reaction and the degree of pain[numerical rating scale(NRS)]in two groups.Results:After treatment,the degree of oral muofcosa reaction in the two groups were both improved when compared with those before treatment(P < 0.05),while the degree of oral muofcosa reaction in the observation group was lower than that in the control group,difference being significant(P<0.05).The proportion of patients whose oral mucosa reaction disappeared after one week of treatment in the observation group was higher than that of the control group,difference being significant(P < 0.01).After treatment,scores of NRS in two groups were both decreased when compared with those before treatment(P < 0.05),while the score of NRS in the observation group was lower than that of the control group(P<0.05).Conclusion:To rinse oral cavity with Kangfuxin liquid can effectively reduce the clinical symptoms of the oral mucosa reaction after radiotherapy of nasopharyngeal carcinoma,reduce and relieve oral pain of patients,and shorten the course of disease.

    参考文献
    相似文献
    引证文献
引用本文

徐小平,郭庆敏,姜贻乾,安素红,苏芳.康复新液干预鼻咽癌放射性治疗后口腔黏膜反应临床观察[J].新中医,2018,50(6):182-184

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2018-06-05
  • 出版日期: