活血下胚汤辅助治疗输卵管妊娠临床观察
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R714.22+1

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浙江省自然科学基金项目(LY14H120129)


Clinical Observation of Huoxue Xiapei Tang in Adjuvant Treatment of Tubal Pregnancy
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    摘要:

    目的:观察活血下胚汤辅助治疗输卵管妊娠的临床疗效。方法:将90例输卵管妊娠患者随机分为联合组与西医组各45例。西医组给予腹腔镜下输卵管开窗术治疗,联合组术后辅以活血下胚汤治疗。7天为1疗程,2组均治疗2疗程。对比分析2组治疗前后血人绒毛膜促性腺激素(β-HCG)的变化,评估治疗效果,记录患者治疗前后输卵管通畅情况及不良反应发生情况。结果:治疗1疗程,2组血β-HCG水平均较治疗前降低(P<0.01);组间比较,差异无统计学意义(P<0.05)。治疗2疗程,2组血β-HCG水平均较治疗1疗程时降低(P<0.01);联合组血β-HCG水平低于西医组(P<0.01)。联合组血β-HCG水平恢复正常所需时间短于西医组,差异有统计学意义(P<0.01)。联合组显效率77.78%,对照组显效率46.67%,2组比较,差异有统计学意义(P<0.01)。治疗后,2组患侧输卵管通畅率均较治疗前升高,差异均有统计学意义(P<0.01);联合组患侧输卵管通畅率高于西医组,差异有统计学意义(P<0.05)。2组胃肠道反应、口腔溃疡、骨髓抑制及肝功能损害发生率比较,差异均无统计学意义(P<0.05)。结论:活血下胚汤辅助腹腔镜下输卵管开窗术治疗输卵管妊娠患者,能提高治疗效果。

    Abstract:

    Objective: To observe the clinical effect of Huoxue Xiapei tang in adjuvant treatment of tubal pregnancy.Methods:Divided 90 cases of patients with tubal pregnancy into the combination group and the western medicine group randomly,45 cases in each group.The western medicine group was given laparoscopic oviduct fenestration for treatment,while the combination group was additionally given Huoxue Xiapei tang for treatment.The treatment lasted for two courses,which covered 7 days in one course.Compared and analyzed the changes of human chorionic gonadotropin(β-HCG)of both groups before and after treatment,evaluated the clinical effect,and recorded the oviductal patency and adverse reactions of patients before and after treatment.Results:After the 1st course of treatment,the levels of β-HCG in both groups were lower than those before treatment(P<0.01);there was no significant difference being found in the inter-group comparison(P<0.05).After the 2nd course of treatment,the levels of β-HCG in both groups were lower than those in the 1st course of treatment(P<0.01);the levels of β-HCG in the combination group were lower than those in the western medicine group(P<0.01).The time for β-HCG returning to the normal level in the combination group was shorter than that in the western medicine group,difference being significant(P<0.01).The obvious effective rate was 77.78%in the combination group and 46.67%in the western medicine group,difference being significant(P<0.01).After treatment,the rates of oviductal patency of the affected side in both groups were higher than those before treatment,difference being significant(P<0.01);the rate of oviductal patency of the affected side in the combination group was higher than that in the western medicine group,difference being significant(P<0.05).There were no significant differences being found in the incidence of gastrointestinal reaction,oral ulcer,spinal inhibition and liver function damage in both groups(P<0.05).Conclusion:The application of Huoxue Xiapei tang assisting laparoscopic oviduct fenestration for tubal pregnancy can promote the clinical effect.

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林乐静,陈丽平.活血下胚汤辅助治疗输卵管妊娠临床观察[J].新中医,2018,50(5):124-127

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  • 在线发布日期: 2018-05-03
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