桂龙咳喘宁片联合西药治疗慢性支气管炎急性发作期痰湿蕴肺证临床疗效分析
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Effect Analysis of Guilong Kechuanning Tablets Combined with Western Medicine for Syndrome of Phlegm-damp Amassing in Lung in Acute Exacerbation of Chronic Bronchitis
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    摘要:

    目的:观察桂龙咳喘宁片联合西药治疗慢性支气管炎急性发作期痰湿蕴肺证的临床疗效。方法:将纳入的慢性支气管炎急性发作期痰湿蕴肺证患者随机分为对照组和观察组。对照组59例服用盐酸氨溴索片,合并感染者加用阿莫西林胶囊,喘息严重者加用氨茶碱口服溶液。观察组58例在对照组治疗的基础上加用桂龙咳喘宁片。2组疗程均为10天。治疗前后评价咳嗽症状积分、痰湿蕴肺证积分、咳嗽视觉模拟评分法(VAS)评分,记录咳嗽缓解时间,评价2组的临床疗效。采用莱塞斯特咳嗽生命质量问卷(LCQ)评定生活质量。结果:愈显率观察组为82.76%,对照组为66.10%,组间比较,差异有统计学意义(P<0.05)。2组白天咳嗽积分、夜间咳嗽积分、总分和咳嗽VAS评分均较治疗前降低(P<0.01),观察组咳嗽积分、总分和咳嗽VAS评分均低于对照组(P<0.01);观察组咳嗽缓解时间短于对照组(P<0.01)。2组LCQ(生理、心理、社会)3个维度评分和总分均较治疗前升高(P<0.01),痰湿蕴肺证积分均较治疗前下降(P<0.01);观察组LCQ各维度评分和总分均高于对照组(P<0.01),痰湿蕴肺证积分低于对照组(P<0.01)。结论:在常规西药基础上加用桂龙咳喘宁片治疗慢性支气管炎急性发作期痰湿蕴肺证患者,可进一步控制咳嗽等症状,提高患者的生活质量,临床疗效优于单纯西药治疗。

    Abstract:

    objective:To observe the clinical effect of Guilong Kechuanning tablets combined with western medicine for syndrome of phlegm-damp amassing in lung in acute exacerbation of chronic bronchitis.Methods:Divided patients with syndrome of phlegm-damp amassing in lung in acute exacerbation of chronic bronchitis into two groups randomly,namely the control group and the observation group,58 cases in each group.Fifty-nine cases in the control group received ambroxol hydrochloride tablets orally,co-infected patients additionally received amoxicillin capsules and patients with severe wheeze additionally received aminophylline oral solution.Fifty-eight cases in the observation group were additionally given Guilong Kechuanning tablets based on the treatment of the control group.The course of treatment for both groups lasted for 10 days.Before and after treatment,analyzed scores of cough symptom,scores of syndrome of phlegm-damp amassing in lung and scores of cough visual analogue scale(VAS),recorded the cough-relieving time,and analyzed the clinical effect in the two groups.Adopted Leicester Cough Questionnaire(LCQ).Results:Good improvement rate in the observation group was 82.76%, and was 66.10%in the control group,difference being significant(P<0.05).Scores of daytime cough,scores of nighttime cough,the total scores and scores of cough VAS in both groups were all lower than those before treatment(P<0.01),and scores of cough,the total scores and scores of cough VAS in the observation group were all lower than those in the control group(P<0.01);the cough-relieving time in the observation group was shorter than that in the control group(P<0.01).Scores of LCQ in three dimensions(physiology,psychology,society)and the total scores in both groups were all higherthan those before treatment(P<0.01),and scores of syndrome of phlegm-damp amassing in lung were lower than those before treatment(P<0.01);scores of LCQ in each dimension and the total scores in the observation group were all higher than those in the control group(P<0.01),and scores of syndrome of phlegm-damp amassing in lung were lower than those in the control group(P<0.01).Conclusion:The additional application of Guilong Kechuanning tablets based on the routine western medicine treating patients with syndrome of phlegm-damp amassing in lung in acute exacerbation of chronic bronchitis can further control symptoms such as cough,improve the life quality of patients,and its clinical effect is better than the pure therapy with western medicine.

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吴仁凯,王杰,徐清喜.桂龙咳喘宁片联合西药治疗慢性支气管炎急性发作期痰湿蕴肺证临床疗效分析[J].新中医,2018,50(5):69-72

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  • 在线发布日期: 2018-05-03
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