消疣汤联合光动力疗法治疗顽固性跖疣临床研究
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R752.5

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Clinical Effect of Xiaoyou Tang Combined with Photodynamic Therapy for Refractory Plantar Wart
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    摘要:

    目的:观察消疣汤联合光动力疗法治疗顽固性跖疣的临床疗效。方法:选取60例顽固性跖疣湿热血瘀证患者随机分成2组各30例,对照组予盐酸氨酮戊酸散光动力联合维A酸乳膏治疗,治疗组在对照组治疗基础上加用消疣汤熏洗,治疗前后观察2组患者跖疣个数、皮损直径、疼痛积分的变化,统计治疗后的临床疗效与1年后的复发情况。结果:治疗2、3月后,治疗组总有效率均高于对照组(P<0.05)。2组跖疣个数均较治疗前减少(P<0.05),跖疣皮损直径均较治疗前缩小(P<0.05),疼痛积分均较治疗前下降(P<0.05);治疗组跖疣个数少于对照组,跖疣皮损直径小于对照组,疼痛积分低于对照组,差异均有统计学意义(P<0.05)。治疗1年后,治疗组复发率13.33%,对照组复发率40.00%,2组比较,差异有统计学意义(P<0.05)。结论:消疣汤联合光动力疗法治疗顽固性跖疣具有较好疗效,能够较大程度地减轻患者的不适感,降低复发率,值得在临床中应用。

    Abstract:

    Objective:To observe the clinical effect of Xiaoyou tang combined with photodynamic therapy for refractory plantar wart.Methods:Selected 60 cases of patients with refractory plantar wart with dampness-heat and blood stasis syndrome and divided them randomly into two groups,30 cases in each group.The control group was given aminolevulinic acid hydrochloride and photodynamic therapy combined with tretinoin ointment,while the treatment group was additionally given fumigation and washing with Xiaoyou tang based on the treatment of the control group.Observed changes of the number of plantar wart,diameter of skin lesions and pain score in two groups before and after treatment,and observed the clinical effect after treatment and recurrence after one year.Results:After treatment of two to three months,the total effective rate in the treatment group was higher than that in the control group(P<0.05).The number of plantar wart in two groups was reduced when compared with that before treatment(P<0.05).The diameter of skin lesions in two groups was smaller than that before treatment(P<0.05).The pain scores in two groups were decreased when compared with those before treatment(P< 0.05).The number of plantar wart in the treatment group was less than that in the control group,diameter of skin lesions was less than that in the control group,and pain scores were less than that in the control group as well,differences being significant(P < 0.05).After treatment of one year,the recurrence rate was 13.33%in the treatment group and was 40.00%in the control group,the difference being significant(P < 0.05).Conclusion:The therapy of Xiaoyou tang combined with photodynamic therapy has good effect in treating refractory plantar wart,which can greatly relieve the malaise of patients and decrease the recurrence rate.The therapy is worthy of clinical application.

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徐艳艳,梁鹏飞,方海萍,李冰.消疣汤联合光动力疗法治疗顽固性跖疣临床研究[J].新中医,2018,50(4):143-146

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  • 在线发布日期: 2018-04-10
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