妇炎舒胶囊联合替硝唑治疗慢性盆腔炎湿热瘀结证临床观察
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R711.33

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Clinical Observation of Fuyanshu Capsules Combined with Tinidazole for Chronic Pelvic Inflammation with Dampness-heat Stasis Syndrome
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    摘要:

    目的:观察妇炎舒胶囊联合替硝唑治疗慢性盆腔炎湿热瘀结证的临床疗效。方法:将80例慢性盆腔炎湿热瘀结证患者随机分为对照组和观察组各40例。对照组给予替硝唑胶囊治疗,观察组在对照组用药基础上加用妇炎舒胶囊。10天为1疗程,2组均连续治疗2疗程。评估2组治疗效果,观察2组治疗前后白细胞介素-2 (IL-2)、肿瘤坏死因子一α(TNF-α)、白细胞介素一10 (IL-10)及中医证候积分的变化,记录不良反应发生情况。结果:观察组总有效率95.00%,高于对照组的75.00%,差异有统计学意义(P<0.05)。治疗后,2组IL-2、IL-10水平均较治疗前上升(P<0.05),TNF-α水平均较治疗前下降(P<0.05);观察组IL-2、IL-10水平均高于对照组(P<0.05),TNF-α/水平低于对照组(P<0.05)。治疗后,2组中医证候积分均较冶疗前降低(P<0.05);观察组中医证候积分低于对照组(P<0.05)。观察组不良反应发生率为12.50%,对照组不良反应发生率为17.50%,2组比较,差异无统计学意义(P>0.05)。结论:妇炎舒胶囊联合替硝唑治疗慢性盆腔炎湿热瘀结证患者,效果优于单纯使用替硝 唑胶囊。

    Abstract:

    Objective: To observe the clinical effect of Fuyanshu capsules combined with tinidazole for chronic pelvic inflammation with dampness-heat stasis syndrome.Methods:Divided 80 cases of patients with chronic pelvic inflammatory disease with dampness-heat stasis syndrome randomly into the control group and the observation group,40 cases in each group.The control group was given tinidazole capsules for treatment,while the observation group was additionally given Fuyanshu capsules based on the medication of the control group.Ten days constituted a course of treatment,and both groups continuously receivedtreatment for 2 courses.Evaluated the efficacy of the two groups,observed changes of levels of interleukin-2(IL-2),tumor necrosis factor(TNF-α)and interleukin-10(IL-10)as well as Chinese medicine syndrome scores before and after treatment, and recorded the adverse reactions.Results The total effective rate was 95.00% in the observation group,higher than that of the control group which was 75.00%(P < 0.05).After treatment,levels of IL-2 and IL-10 in both groups were increased when compared with those before treatment(P< 0.05),while the TNF-α levels in both groups were decreased when compared with those before treatment(P<0.05).Levels of IL-2 and IL-10 in the observation group were higher than those in the control group(P<0.05),while the TNF-α levels were lower than those in the control group(P < 0.05).After treatment,Chinese medicine syndrome scores in both groups were decreased when compared with those before treatment(P<0.05).The Chinese medicine syndrome scores in the observation group were lower than those in the control group(P<0.05).The incidence of adverse reactions was 12.50%in the observation group and was 17.50%in the control group,and there was no significance in the difference(P> 0.05).Conclusion:The efficacy of the therapy of Fuyanshu capsules combined with tinidazole was superior to simple application of tinidazole capsules in treating chronic pelvic inflammation with dampness-heat stasis syndrome.

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张幼萍.妇炎舒胶囊联合替硝唑治疗慢性盆腔炎湿热瘀结证临床观察[J].新中医,2018,50(3):123-126

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  • 在线发布日期: 2018-03-04
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