| 摘要: |
| 目的：观察养胃愈萎汤治疗慢性萎缩性胃炎（CAG）患者的临床疗效与对血清中炎性因子C-反应蛋白（CRP）、白细胞介素-6（IL-6）和肿瘤坏死因子-α（TNF-α）的影响。方法：将确诊为CAG脾胃虚弱证的的86例患者随机分成2组各43例，对照组用维酶素片、克拉霉素分散片、阿莫西林胶囊、奥美拉唑肠溶胶囊进行治疗。治疗组应用养胃愈萎汤进行治疗。2组均治疗3月。观察2组的临床疗效，治疗前后检测血清中CRP、IL-6、TNF-α的水平。结果：疗程结束后，治疗组总有效率为95.35%，对照组总有效率为79.07%，2组比较，差异有统计学意义（P＜0.05）。2组血清CRP、IL-6、TNF-α水平均较治疗前下降（P＜0.05），治疗组3项指标水平均低于对照组（P＜0.05）。结论：养胃愈萎汤治疗CAG脾胃虚弱证患者具有较好的临床疗效，且可减轻慢性炎症反应。 |
| 关键词: 慢性萎缩性胃炎（CAG） 脾胃虚弱证 养胃愈萎汤 C-反应蛋白（CRP） 白细胞介素-6（IL-6） 肿瘤坏死因子-α（TNF-α） |
| DOI： |
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| 基金项目: |
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| Clinical Observation of Yangwei Yuwei Tang for Chronic Atrophic Gastritis with Spleen and Stomach Deficiency Type |
| PANG Chunxia,SHEN Jieru |
| () |
| Abstract: |
| Objective：To observe the curative effect of Yangwei Yuwei tang for chronic atrophic gastritis(CAG)and the effect on inflammatory factor C-reactive protein(CRP)，interleukin-6(IL-6)and tumor necrosis factor-α(TNF-α).Methods：Selected 86 cases of patients diagnosed with CAG of spleen and stomach deficiency type，and divided them into two groups randomly， 43 cases in each group.The control group was given vitacoenzyme tablets， clarithromycin disperse tablets，amoxicillin capsules，and omeprazole enteric-coated capsules，while the treatment group was given Yangwei Yuwei tang.Both groups
receivedtreatment for three months.Observed the curative effect and levels of CRP，IL-6 and TNF-αin the two groups before and after treatment.Results：After treatment，the total effective rate was 95.35%in the treatment group and 79.07%in the control group，the difference being significant(P＜0.05).Levels of serum CRP，IL-6 and TNF-α of both groups were decreased when compared with those before treatment(P＜0.05)，and levels of the three indexes in the treatment group were lower than those in the control group(P＜0.05).Conclusion：Yangwei Yuwei tang has good clinical effect for CAG patients with spleen and stomach deficiency syndrome，and it can reduce chronic inflammatory response. |
| Key words: Chronicatrophicgastritis(CAG) Spleenandstomachdeficiency syndrome Yangwei Yuwei tang C-reactive protein(CRP) Interleukin-6(IL-6) Tumor necrosis factor- α(TNF-α) |
