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| 逍遥散抗抑郁的临床与实验研究进展 |
| 梁媛,赵晖,岳利峰,李玉波,王筠,李志更,岳广欣,黄晓华,滕静如 |
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| (中国中医科学院中医基础理论研究所中国中医科学院科研处北京中医药大学东直门医院) |
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| 摘要: |
| 近10年来,诸多医家在临床与实验方面对逍遥散抗抑郁的作用进行了大量研究。从流行病学调查来看,逍遥散作为治疗抑郁症的基础方,临床广泛应用于中风后抑郁、产后抑郁、乳腺癌伴抑郁、轻中度抑郁、更年期抑郁症等并取得较好疗效。实验研究也发现,逍遥散通过影响神经递质及其受体、下丘脑-垂体-肾上腺轴、细胞分子机制、细胞因子等发挥抗抑郁作用。 |
| 关键词: 抑郁症 逍遥散 文献综述 |
| DOI： |
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| 基金项目:国家自然科学基金资助项目（81573846；81603516；81603417） |
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| Abstract: |
| In clinical practice and experiment，much research had been carried through on the effect of Xiaoyao powder in treating depression in the recent 10 years.From the investigation in epidemiology，as a basic prescription for depression，Xiaoyao powder is widely applied in treating post-stroke depression，postpartum depression，breast cancer with depression，mild and moderate depression and menopause depression，and has good efficacy.Experimental research also finds that Xiaoyao powder exerts action of anti-depression by affecting neurotransmitter and its receptor，hypothalamic-pituitaryadrenal axis，cellular and molecular mechanisms and cytokine. |
| Key words: Depression Xiaoyao powder Literature review |
