| 摘要: |
| 目的:观察中西医结合治疗中青年肝郁脾虚型不寐患者的临床疗效。方法:纳入92例中青年肝郁脾虚型不寐患者,随机分为治疗组和对照组各46例。治疗组给予疏肝补脾汤联合艾司唑仑片治疗,对照组仅予艾司唑仑片治疗。治疗时间均为2月。在治疗前、治疗1月及治疗2月分别采用匹兹堡睡眠质量指数(PSQI)对2组患者进行睡眠质量的评价。比较2组的临床疗效。结果:治疗后,治疗组总有效率78.26%,对照组总有效率56.52%,2组比较,差异有统计学意义(P<0.05)。治疗组治疗1月、2月后的PSQI均较治疗前降低,治疗2月的PSQI较治疗1月亦有所降低,差异均有统计学意义(P<0.05)。对照组治疗前后的PSQI比较,差异均无统计学意义(P>0.05)。治疗1月、2月,2组PSQI比较,差异均有统计学意义(P<0.05)。结论:疏肝补脾汤联合艾司唑仑片治疗中青年肝郁脾虚型不寐患者可提高睡眠质量,疗效优于单纯服用艾司唑仑片。 |
| 关键词: 不寐 失眠 中青年 肝郁脾虚证 中西医结合疗法 疏肝补脾汤 艾司唑仑片 匹兹堡睡眠质量指数(PSQI) |
| DOI： |
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| 基金项目:浙江省中医药科技计划项目（2015ZA097） |
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| Abstract: |
| Objective：To observe the effect of integrated Chinese and western medicine therapy for young andmiddle-aged sleeplessness patients with liver depression and spleen deficiency type.Methods：Selected 92 young and middle-aged insomnia patients with liver depression and spleen deficiency type，and divided them into the treatment group and the control group being 46 cases in each randomly.The treatment group was treated with Shugan Bupi tang combined with estazolam tablets，while the control group was treated with estazolam tablets only.Treatment for both groups lasted for two weeks.Evaluated sleeping quality of both groups with Pittsburgh sleep quality index(PSQI)before treatment，one month after treatment and two months after treatment.Compared clinical effect of both groups.Results：After treatment，the total effective rate was 78.26%in the treatment group，and was 56.52%in the control group，the difference being significant(P＜0.05).One and two months after treatment，PSQI scores of the treatment group were lower than those before treatment，and PSQI scores of two months after treatment were lower than those one month after treatment，differences being significant(P＜0.05).Compared PSQI scores of the control group before and after treatment，the difference had no significance(P＞0.05).Compared PSQI scores between the two groups one month and two months after treatment，differences were significant(P＜0.05).Conclusion：The combination of Shugan Bupi tang and estazolam tablets can improve sleep quality of sleeplessness patients with liver depression and spleen deficiency，which has better efficacy than taking estazolam tablets only. |
| Key words: Insomnia Young and middle-aged Liver depression and spleen deficiency type Integrated Chinese and western medicine therapy Shugan Bupi tang Estazolam tablets Pittsburgh sleep quality index(PSQI) |
